DDX21 cdna clone
DDX21 cDNA Clone
NCBI and Uniprot Product Information
NCBI Description
DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein, which is an antigen recognized by autoimmune antibodies from a patient with watermelon stomach disease. This protein unwinds double-stranded RNA, folds single-stranded RNA, and may play important roles in ribosomal RNA biogenesis, RNA editing, RNA transport, and general transcription. [provided by RefSeq, Jul 2008]
Uniprot Description
DDX21: a protein of the DEAD box helicase family. Unwinds double-stranded RNA, folds single-stranded RNA, and may play important roles in ribosomal RNA biogenesis, RNA editing, RNA transport, and general transcription. DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp, are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly.
Protein type: Nucleolus; EC 3.6.4.13; RNA-binding; Helicase; RNA processing
Chromosomal Location of Human Ortholog: 10q21
Cellular Component: membrane; nucleolus; nucleoplasm; nucleus
Molecular Function: ATP-dependent RNA helicase activity; protein binding; rRNA binding; snoRNA binding
Biological Process: osteoblast differentiation; positive regulation of gene expression, epigenetic; RNA secondary structure unwinding; transcription from RNA polymerase II promoter
Research Articles on DDX21
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Product Notes
The DDX21 ddx21 (Catalog #AAA1274674) is a cDNA Clone and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: atgaattctc ctaaatccaa aaaggcaaaa aagaaagagg agccatctca aaatgacatt tctcctaaaa ccaaaagttt gagaaagaaa aaggagccca ttgaaaagaa agtggtttct tctaaaacca aaaaagtgac aaaaaatgag gagccttctg aggaagaaat agatgctcct aagcccaaga agatgaagaa agaaaaggaa atgaatggag aaactagaga gaaaagcccc aaactgaaga atggatttcc tcatcctgaa ccggactgta accccagtga agctgccagt gaagaaagta acagtgagat agagcaggaa atacctgtgg aacaaaaaga aggcgctttc tctaattttc ccatatctga agaaactatt aaacttctca aaggccgagg agtgaccttc ctatttccta tacaagcaaa gacattccat catgtttaca gcgggaagga cttaattgca caggcacgga caggaactgg gaagacattc tcctttgcca tccctttgat tgagaaactt catggggaac tgcaagacag gaagagaggc cgtgcccctc aggtactggt tcttgcacct acaagagagt tggcaaatca agtaagcaaa gacttcagtg acatcacaaa aaagctgtca gtggcttgtt tttatggtgg aactccctat ggaggtcaat ttgaacgcat gaggaatggg attgatatcc tggttggaac accaggtcgt atcaaagacc acatacagaa tggcaaacta gatctcacca aacttaagca tgttgtcctg gatgaagtgg accagatgtt ggatatggga tttgctgatc aagtggaaga gattttaagt gtggcataca agaaagattc tgaagacaat ccccaaacat tgcttttttc tgcaacttgc cctcattggg tatttaatgt tgccaagaaa tacatgaaat ctacatatga acaggtggac ctgattggta aaaagactca gaaaacggca ataactgtgg agcatctggc tattaagtgc cactggactc agagggcagc agttattggg gatgtcatcc gagtatatag tggtcatcaa ggacgcacta tcatcttttg tgaaaccaag aaagaagccc aggagctgtc ccagaattca gctataaagc aggatgctca gtccttgcat ggagacattc cacagaagca aagggaaatc accctgaaag gttttagaaa tggtagtttt ggagttttgg tggcaaccaa tgttgctgca cgtgggttag acatccctga ggttgatttg gttatacaaa gctctccacc aaaggatgta gagtcctaca ttcatcgatc cgggcggaca ggcagagctg gaaggacggg ggtgtgcatc tgcttttatc agcacaagga agaatatcag ttagtacaag tggagcaaaa agcgggaatt aagttcaaac gaataggtgt tccttctgca acagaaataa taaaagcttc cagcaaagat gccatcaggc ttttggattc cgtgcctccc actgccatta gtcacttcaa acaatcagct gagaagctga tagaggagaa gggagctgtg gaagctctgg cagcagcact ggcccatatt tcaggtgcca cgtccgtaga ccagcgctcc ttgatcaact caaatgtggg ttttgtgacc atgatcttgc agtgctcaat tgaaatgcca aatattagtt atgcttggaa agaacttaaa gagcagctgg gcgaggagat tgattccaaa gtgaagggaa tggtttttct caaaggaaag ctgggtgttt gctttgatgt acctaccgca tcagtaacag aaatacagga gaaatggcat gattcacgac gctggcagct ctctgtggcc acagagcaac cagaactgga aggaccacgg gaaggatatg gaggcttcag gggacagcgg gaaggcagtc gaggcttcag gggacagcgg gacggaaaca gaagattcag aggacagcgg gaaggcagta gaggcccgag aggacagcga tcaggaggtg gcaacaaaag taacagatcc caaaacaaag gccagaagcg gagtttcagt aaagcatttg gtcaataa. It is sometimes possible for the material contained within the vial of "DDX21, cDNA Clone" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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