CXCL10 cdna clone
CXCL10 cDNA Clone
NCBI and Uniprot Product Information
NCBI Description
This antimicrobial gene encodes a chemokine of the CXC subfamily and ligand for the receptor CXCR3. Binding of this protein to CXCR3 results in pleiotropic effects, including stimulation of monocytes, natural killer and T-cell migration, and modulation of adhesion molecule expression. [provided by RefSeq, Sep 2014]
Uniprot Description
CXCL10: Chemotactic for monocytes and T-lymphocytes. Binds to CXCR3. Belongs to the intercrine alpha (chemokine CxC) family.
Protein type: Motility/polarity/chemotaxis; Chemokine; Secreted; Secreted, signal peptide
Chromosomal Location of Human Ortholog: 4q21
Cellular Component: extracellular region; extracellular space
Molecular Function: cAMP-dependent protein kinase regulator activity; chemokine activity; CXCR3 chemokine receptor binding; heparin binding; protein binding; receptor binding
Biological Process: blood circulation; cell surface receptor linked signal transduction; cell-cell signaling; chemotaxis; endothelial cell activation; G-protein coupled receptor protein signaling pathway; immune response; muscle development; positive regulation of cAMP metabolic process; positive regulation of release of sequestered calcium ion into cytosol; positive regulation of transcription from RNA polymerase II promoter; regulation of cell proliferation; signal transduction
Research Articles on CXCL10
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Product Notes
The CXCL10 cxcl10 (Catalog #AAA1274380) is a cDNA Clone and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: atgaatcaaa ctgccattct gatttgctgc cttatctttc tgactctaag tggcattcaa ggagtacctc tctctagaac tgtacgctgt acctgcatca gcattagtaa tcaacctgtt aatccaaggt ctttagaaaa acttgaaatt attcctgcaa gccaattttg tccacgtgtt gagatcattg ctacaatgaa aaagaagggt gagaagagat gtctgaatcc agaatcgaag gccatcaaga atttactgaa agcagttagc aaggaaaggt ctaaaagatc tccttaa. It is sometimes possible for the material contained within the vial of "CXCL10, cDNA Clone" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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