CPSF1 cdna clone
CPSF1 cDNA Clone
Gene Names
CPSF1; CPSF160; P/cl.18; HSU37012
Synonyms
CPSF1; CPSF1 cDNA Clone; CPSF1 cdna clone
Sequence
atgtacgccgtgtacaaacaggcgcatccgcccaccggtctggagttctccatgtactgcaacttcttcaacaacagcgagcgcaacctggtagtggccgggacctcgcagctctacgtgtaccgcctcaaccgcgacgccgaggctctgaccaagaatgacaggagcacagaggggaaggcccaccgggagaagctcgagcttgctgcctccttctccttctttggcaacgtcatgtccatggccagcgtgcagctggcaggagccaagcgggatgccctgctcctaagcttcaaggatgccaagctgtctgtggtggagtacgacccgggcacccatgacctgaagaccctgtcactgcactactttgaggagcctgagcttcgggacgggtttgtgcagaatgtacacacgccgcgagtgcgggtggaccccgacgggcgctgtgcagccatgcttgtctacggcacgcggctggtggtcctgcccttccgcagggagagcctggctgaggagcacgaggggctcgtgggtgaggggcagaggtccagcttcctgcccagctacatcatcgacgtgcgggccctagacgagaagctgctcaacatcatcgacctgcagttcctgcatggctactacgagcctaccctcctcatcctgtttgagcccaaccagacctggcctgggcgcgtggccgtgcggcaggacacgtgctccattgtggccatctcactgaacatcacgcagaaggtgcaccccgtcatctggtccctcaccagcctgccctttgactgcacccaggctctggctgtgcccaagcccataggtggggtggtggtgtttgccgtcaactcgctgttgtacctgaaccagagcgtccccccgtatggcgtggctctcaacagcctcaccacaggaaccacggctttcccgcttcgcacccaggagggtgtgcggatcaccctggactgcgcccaggccaccttcatctcctacgacaagatggtcatctccctcaagggcggcgagatctacgtgctgaccctcatcaccgacggcatgcgcagtgtccgagcgttccactttgacaaggcggccgccagcgtcctcaccaccagcatggtcaccatggagcccgggtacctgttcctgggttctcgcctgggcaattccctcctcctcaagtacacggagaagctgcaggagcccccggccagtgctgtccgtgaggctgccgacaaggaagagcctccctcaaagaagaagcgagtggatgcgacggccggctggtcagctgcgggtaagtcggtgccgcaggatgaggtggacgagattgaagtgtacggcagcgaggcccagtcgggaacacagctggccacctactcctttgaggtgtgtgacagcatcctgaacattggaccctgtgccaatgccgccgtgggcgagcctgccttcctctctgaagagtttcagaacagccccgagccggacctggagattgtggtttgctccggccacgggaagaacggggctttgtcggtgctgcagaagagcatccggccccaggtggtgacaacctttgagcttcccggctgctatgacatgtggacagtcatcgccccggtgcgtaaggaggaggaggacaatcccaagggggagggcacagagcaggaacccagcaccacccctgaagcagacgacgacggccgcagacacggattcctgattctgagccgggaagactccaccatgatcctgcagacggggcaggagatcatggagctggacaccagtggcttcgccactcagggccccacggtctttgctgggaacatcggggacaaccgctacattgtccaagtgtcaccactgggcatccgcctgctggaaggagtgaatcagctgcacttcatccccgtggacctgggcgcccccatcgtgcagtgcgccgtggccgacccctatgtggtcatcatgagtgccgagggccacgtcaccatgttcctgctgaagagtgactcctacggtggccgccaccaccgcctggcgctgcacaagcccccgctgcaccatcagtccaaggtgattacgctgtgcctgtaccgagacctcagcggcatgttcaccactgagagccgcctgggtggggcccgtgacgagctcgggggccgcagtggcccggaggccgagggcctgggctcagagactagccccacagtggatgacgaggaggagatgctgtatggggattcgggctccctcttcagccccagcaaggaggaggcccgaagaagcagccagccccctgctgaccgggaccctgcacccttccgggcagagcctacccactggtgcctgctggtgcgggagaatggcaccatggagatctaccagcttcccgactggcggctggtgttcctggtgaagaacttccctgtggggcagcgggtccttgtggacagctcctttggacagcccactacacagggcgaggcccgcagggaggaggccacgcgccagggggagctgcccctcgtcaaggaggtgctgctggtggcgctgggcagccgccagagcaggccctacctgctggtgcatgtggaccaagagctgcttatctacgaggccttcccccacgactctcagctcggccagggcaatctcaaagtccgctttaagaaggtccctcacaacatcaacttccgtgagaagaagccaaagccatccaagaagaaagcagaaggtggcggcgcagaggagggggctggggcccggggccgcgtggcgcgtttccgctacttcgaggatatttatggctactcaggggtcttcatctgcggcccctcccctcactggctcttggtgaccggccgaggggctctgcggctacaccccatggccatcgacggcccggtcgactctttcgctccattccacaatgtcaactgtccccgcggcttcctgtacttcaacagacagggcgagctgaggatcagtgtcctgcctgcctacctgtcctatgatgccccatggcctgtcaggaagatcccgctgcgctgcacggcccactatgtggcttaccacgtggagtctaaggtgtatgctgtggccaccagcaccaacacgccgtgtgcccgcatcccacgcatgactggcgaggagaaggagtttgagaccatcgagagagatgagcggtacatccacccccagcaggaggccttctccatccagctcatctccccggtcagctgggaggctattcccaatgccaggatcgagctgcaggagtgggagcatgtgacctgcatgaagacagtgtctctgcgcagtgaggagaccgtgtcgggcctcaaaggctacgtggccgccgggacctgcctcatgcagggggaggaggtcacgtgccgagggcggatcttgatcatggatgtgattgaggtggtgcccgagcctggccagcccttgaccaagaacaagttcaaagtcctttacgagaaggagcagaaggggcccgtgaccgccctgtgccactgcaatggccacctggtgtcggccatcggccagaagattttcctgtggagcctgcgggccagcgagctgacgggcatggccttcatcgacacgcagctctacatacaccagatgatcagcgtcaagaacttcatcctggcagccgacgtcatgaagagcatttcgctgctgcgctaccaggaggaaagcaagacgctgagcctggtgtcgcgggatgccaagcccctggaggtgtacagcgtggacttcatggtggacaatgcccagctgggttttctggtgtctgaccgcgaccgcaacctcatggtgtacatgtacctgcccgaagccaaggagagtttcgggggcatgcgcctgctgcgtcgggcagacttccacgtgggtgcccacgtgaacacgttctggaggaccccgtgccggggggccactgaagggctcagcaaaaagtcggtcgtgtgggagaataagcacatcacgtggtttgccaccctggacggcggcatcgggctgctgctgcccatgcaggagaagacctaccggcggctgctgatgctgcagaacgcgctgaccaccatgctgccacaccacgccggcctcaacccccgcgccttccggatgctgcacgtggaccgccgcaccctccagaatgccgtgcgcaacgtgctggatggggagctgctcaaccgctacctgtacctgagcaccatggagcgcagcgagctagccaagaagatcggcaccacaccagacataatcctggacgacttgctggagacggaccgcgtcaccgcccacttctag
Sequence Length
4332
Vector
Please Inquire
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
160,884 Da
NCBI Official Full Name
Homo sapiens cleavage and polyadenylation specific factor 1, 160kDa, mRNA
NCBI Official Synonym Full Names
cleavage and polyadenylation specific factor 1
NCBI Official Symbol
CPSF1
NCBI Official Synonym Symbols
CPSF160; P/cl.18; HSU37012
NCBI Protein Information
cleavage and polyadenylation specificity factor subunit 1
UniProt Protein Name
Cleavage and polyadenylation specificity factor subunit 1
UniProt Gene Name
CPSF1
UniProt Synonym Gene Names
CPSF160; CPSF 160 kDa subunit
UniProt Entry Name
CPSF1_HUMAN
NCBI Description
Cleavage and polyadenylation specificity factor (CPSF) is a multisubunit complex that plays a central role in 3-prime processing of pre-mRNAs. CPSF recognizes the AAUAAA signal in the pre-mRNA and interacts with other proteins to facilitate both RNA cleavage and poly(A) synthesis. CPSF1 is the largest subunit of the CPSF complex (Murthy and Manley, 1995 [PubMed 7590244]).[supplied by OMIM, Mar 2008]
Uniprot Description
CPSF1: Component of the cleavage and polyadenylation specificity factor (CPSF) complex that plays a key role in pre- mRNA 3'-end formation, recognizing the AAUAAA signal sequence and interacting with poly(A) polymerase and other factors to bring about cleavage and poly(A) addition. This subunit is involved in the RNA recognition step of the polyadenylation reaction. Belongs to the CPSF1 family.
Protein type: RNA-binding; RNA splicing
Chromosomal Location of Human Ortholog: 8q24.23
Cellular Component: mRNA cleavage and polyadenylation specificity factor complex; nucleoplasm
Molecular Function: enzyme binding; protein binding
Biological Process: mRNA 3'-end processing; mRNA cleavage; mRNA export from nucleus; mRNA polyadenylation; nuclear mRNA splicing, via spliceosome; termination of RNA polymerase II transcription; tRNA splicing
Research Articles on CPSF1
Similar Products
Product Notes
The CPSF1 cpsf1 (Catalog #AAA1269471) is a cDNA Clone and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: atgtacgccg tgtacaaaca ggcgcatccg cccaccggtc tggagttctc catgtactgc aacttcttca acaacagcga gcgcaacctg gtagtggccg ggacctcgca gctctacgtg taccgcctca accgcgacgc cgaggctctg accaagaatg acaggagcac agaggggaag gcccaccggg agaagctcga gcttgctgcc tccttctcct tctttggcaa cgtcatgtcc atggccagcg tgcagctggc aggagccaag cgggatgccc tgctcctaag cttcaaggat gccaagctgt ctgtggtgga gtacgacccg ggcacccatg acctgaagac cctgtcactg cactactttg aggagcctga gcttcgggac gggtttgtgc agaatgtaca cacgccgcga gtgcgggtgg accccgacgg gcgctgtgca gccatgcttg tctacggcac gcggctggtg gtcctgccct tccgcaggga gagcctggct gaggagcacg aggggctcgt gggtgagggg cagaggtcca gcttcctgcc cagctacatc atcgacgtgc gggccctaga cgagaagctg ctcaacatca tcgacctgca gttcctgcat ggctactacg agcctaccct cctcatcctg tttgagccca accagacctg gcctgggcgc gtggccgtgc ggcaggacac gtgctccatt gtggccatct cactgaacat cacgcagaag gtgcaccccg tcatctggtc cctcaccagc ctgccctttg actgcaccca ggctctggct gtgcccaagc ccataggtgg ggtggtggtg tttgccgtca actcgctgtt gtacctgaac cagagcgtcc ccccgtatgg cgtggctctc aacagcctca ccacaggaac cacggctttc ccgcttcgca cccaggaggg tgtgcggatc accctggact gcgcccaggc caccttcatc tcctacgaca agatggtcat ctccctcaag ggcggcgaga tctacgtgct gaccctcatc accgacggca tgcgcagtgt ccgagcgttc cactttgaca aggcggccgc cagcgtcctc accaccagca tggtcaccat ggagcccggg tacctgttcc tgggttctcg cctgggcaat tccctcctcc tcaagtacac ggagaagctg caggagcccc cggccagtgc tgtccgtgag gctgccgaca aggaagagcc tccctcaaag aagaagcgag tggatgcgac ggccggctgg tcagctgcgg gtaagtcggt gccgcaggat gaggtggacg agattgaagt gtacggcagc gaggcccagt cgggaacaca gctggccacc tactcctttg aggtgtgtga cagcatcctg aacattggac cctgtgccaa tgccgccgtg ggcgagcctg ccttcctctc tgaagagttt cagaacagcc ccgagccgga cctggagatt gtggtttgct ccggccacgg gaagaacggg gctttgtcgg tgctgcagaa gagcatccgg ccccaggtgg tgacaacctt tgagcttccc ggctgctatg acatgtggac agtcatcgcc ccggtgcgta aggaggagga ggacaatccc aagggggagg gcacagagca ggaacccagc accacccctg aagcagacga cgacggccgc agacacggat tcctgattct gagccgggaa gactccacca tgatcctgca gacggggcag gagatcatgg agctggacac cagtggcttc gccactcagg gccccacggt ctttgctggg aacatcgggg acaaccgcta cattgtccaa gtgtcaccac tgggcatccg cctgctggaa ggagtgaatc agctgcactt catccccgtg gacctgggcg cccccatcgt gcagtgcgcc gtggccgacc cctatgtggt catcatgagt gccgagggcc acgtcaccat gttcctgctg aagagtgact cctacggtgg ccgccaccac cgcctggcgc tgcacaagcc cccgctgcac catcagtcca aggtgattac gctgtgcctg taccgagacc tcagcggcat gttcaccact gagagccgcc tgggtggggc ccgtgacgag ctcgggggcc gcagtggccc ggaggccgag ggcctgggct cagagactag ccccacagtg gatgacgagg aggagatgct gtatggggat tcgggctccc tcttcagccc cagcaaggag gaggcccgaa gaagcagcca gccccctgct gaccgggacc ctgcaccctt ccgggcagag cctacccact ggtgcctgct ggtgcgggag aatggcacca tggagatcta ccagcttccc gactggcggc tggtgttcct ggtgaagaac ttccctgtgg ggcagcgggt ccttgtggac agctcctttg gacagcccac tacacagggc gaggcccgca gggaggaggc cacgcgccag ggggagctgc ccctcgtcaa ggaggtgctg ctggtggcgc tgggcagccg ccagagcagg ccctacctgc tggtgcatgt ggaccaagag ctgcttatct acgaggcctt cccccacgac tctcagctcg gccagggcaa tctcaaagtc cgctttaaga aggtccctca caacatcaac ttccgtgaga agaagccaaa gccatccaag aagaaagcag aaggtggcgg cgcagaggag ggggctgggg cccggggccg cgtggcgcgt ttccgctact tcgaggatat ttatggctac tcaggggtct tcatctgcgg cccctcccct cactggctct tggtgaccgg ccgaggggct ctgcggctac accccatggc catcgacggc ccggtcgact ctttcgctcc attccacaat gtcaactgtc cccgcggctt cctgtacttc aacagacagg gcgagctgag gatcagtgtc ctgcctgcct acctgtccta tgatgcccca tggcctgtca ggaagatccc gctgcgctgc acggcccact atgtggctta ccacgtggag tctaaggtgt atgctgtggc caccagcacc aacacgccgt gtgcccgcat cccacgcatg actggcgagg agaaggagtt tgagaccatc gagagagatg agcggtacat ccacccccag caggaggcct tctccatcca gctcatctcc ccggtcagct gggaggctat tcccaatgcc aggatcgagc tgcaggagtg ggagcatgtg acctgcatga agacagtgtc tctgcgcagt gaggagaccg tgtcgggcct caaaggctac gtggccgccg ggacctgcct catgcagggg gaggaggtca cgtgccgagg gcggatcttg atcatggatg tgattgaggt ggtgcccgag cctggccagc ccttgaccaa gaacaagttc aaagtccttt acgagaagga gcagaagggg cccgtgaccg ccctgtgcca ctgcaatggc cacctggtgt cggccatcgg ccagaagatt ttcctgtgga gcctgcgggc cagcgagctg acgggcatgg ccttcatcga cacgcagctc tacatacacc agatgatcag cgtcaagaac ttcatcctgg cagccgacgt catgaagagc atttcgctgc tgcgctacca ggaggaaagc aagacgctga gcctggtgtc gcgggatgcc aagcccctgg aggtgtacag cgtggacttc atggtggaca atgcccagct gggttttctg gtgtctgacc gcgaccgcaa cctcatggtg tacatgtacc tgcccgaagc caaggagagt ttcgggggca tgcgcctgct gcgtcgggca gacttccacg tgggtgccca cgtgaacacg ttctggagga ccccgtgccg gggggccact gaagggctca gcaaaaagtc ggtcgtgtgg gagaataagc acatcacgtg gtttgccacc ctggacggcg gcatcgggct gctgctgccc atgcaggaga agacctaccg gcggctgctg atgctgcaga acgcgctgac caccatgctg ccacaccacg ccggcctcaa cccccgcgcc ttccggatgc tgcacgtgga ccgccgcacc ctccagaatg ccgtgcgcaa cgtgctggat ggggagctgc tcaaccgcta cctgtacctg agcaccatgg agcgcagcga gctagccaag aagatcggca ccacaccaga cataatcctg gacgacttgc tggagacgga ccgcgtcacc gcccacttct ag. It is sometimes possible for the material contained within the vial of "CPSF1, cDNA Clone" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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