CMAS cdna clone
CMAS cDNA Clone
NCBI and Uniprot Product Information
NCBI Description
This gene encodes an enzyme that converts N-acetylneuraminic acid (NeuNAc) to cytidine 5'-monophosphate N-acetylneuraminic acid (CMP-NeuNAc). This process is important in the formation of sialylated glycoprotein and glycolipids. This modification plays a role in cell-cell communications and immune responses. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2016]
Uniprot Description
CMAS: Catalyzes the activation of N-acetylneuraminic acid (NeuNAc) to cytidine 5'-monophosphate N-acetylneuraminic acid (CMP-NeuNAc), a substrate required for the addition of sialic acid. Has some activity toward NeuNAc, N-glycolylneuraminic acid (Neu5Gc) or 2-keto-3-deoxy-D-glycero-D-galacto-nononic acid (KDN). Belongs to the CMP-NeuNAc synthase family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: EC 2.7.7.43; Transferase; Carbohydrate Metabolism - amino sugar and nucleotide sugar
Chromosomal Location of Human Ortholog: 12p12.1
Cellular Component: cytosol; membrane; nucleoplasm; nucleus
Molecular Function: N-acylneuraminate cytidylyltransferase activity
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Product Notes
The CMAS cmas (Catalog #AAA1269313) is a cDNA Clone and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: atggactcgg tggagaaggg ggccgccacc tccgtctcca acccgcgggg gcgaccgtcc cggggccggc cgccgaagct gcagcgcaac tctcgcggcg gccagggccg aggtgtggag aagcccccgc acctggcagc cctaattctg gcccggggag gcagcaaagg catccccctg aagaacatta agcacctggc gggggtcccg ctcattggct gggtcctgcg tgcggccctg gattcagggg ccttccagag tgtatgggtt tcgacagacc atgatgaaat tgagaatgtg gccaaacaat ttggtgcaca agttcatcga agaagttctg aagtttcaaa agacagctct acctcactag atgccatcat agaatttctt aattatcata atgaggttga cattgtagga aatattcaag ctacttctcc atgtttacat cctactgatc ttcaaaaagt tgcagaaatg attcgagaag aaggatatga ttctgttttc tctgttgtga gacgccatca gtttcgatgg agtgaaattc agaaaggagt tcgtgaagtg accgaacctc tgaatttaaa tccagctaaa cggcctcgtc gacaagactg ggatggagaa ttatatgaaa atggctcatt ttattttgct aaaagacatt tgatagagat gggttacttg cagggtggaa aaatggcata ctacgaaatg cgagctgaac atagtgtgga tatagatgtg gatattgatt ggcctattgc agagcaaaga gtattaaggt ga. It is sometimes possible for the material contained within the vial of "CMAS, cDNA Clone" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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