CER1 cdna clone
CER1 cDNA Clone
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a cytokine member of the cysteine knot superfamily, characterized by nine conserved cysteines and a cysteine knot region. The cerberus-related cytokines, together with Dan and DRM/Gremlin, represent a group of bone morphogenetic protein (BMP) antagonists that can bind directly to BMPs and inhibit their activity. [provided by RefSeq, Jul 2008]
Uniprot Description
CER1: Cytokine that may play a role in anterior neural induction and somite formation during embryogenesis in part through a BMP-inhibitory mechanism. Can regulate Nodal signaling during gastrulation as well as the formation and patterning of the primitive streak. Belongs to the DAN family.
Protein type: Secreted, signal peptide; Secreted; Motility/polarity/chemotaxis
Chromosomal Location of Human Ortholog: 9p23-p22
Cellular Component: extracellular region; extracellular space
Molecular Function: morphogen activity; protein homodimerization activity
Biological Process: anterior/posterior axis specification; anterior/posterior pattern formation; BMP signaling pathway; bone mineralization; cell migration involved in gastrulation; determination of dorsal identity; gastrulation; negative regulation of activin receptor signaling pathway; negative regulation of BMP signaling pathway; negative regulation of cell proliferation; negative regulation of Wnt receptor signaling pathway; nervous system development; ureteric bud development
Research Articles on CER1
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Product Notes
The CER1 cer1 (Catalog #AAA1271620) is a cDNA Clone and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: atgcatctcc tcttatttca gctgctggta ctcctgcctc taggaaagac cacatggcac caggatggcc gccagaatca gagttctctt tcccccgtac tcctgccaag gaatcaaaga gagcttccca caggcaacca tgaggaagct gaggagaagc cagatctgct tgtcgcagtg ccacaccttg taggcaccag ccctgcaggg gaaggccaga ggcagagaga gaagatgctg tccagatttg gcaggttctg gaagaagcct gagagagaaa tgcatccatc cagggactca gatagtgagc ccttcccacc tgggacccag tccctcatcc agccgataga tggaatgaaa atggagaaat ctcctcttcg ggaagaagcc aagaaattct ggcaccactt catgttcaga aaaactccgg cttctcaggg ggtcatcttg cccatcaaaa gccatgaagt acattgggag acctgcagga cagtgccctt cagccagact ataacccacg aaggctgtga aaaaatagtt gttcagaaca acctttgctt tgggaaatgc gggtctgttc attttcctgg agccgcgcag cactcccata cctcctgctc tcactgtttg cctgccaagt tcaccacgat gcacttgcca ctgaactgca ctgaactttc ctccgtgatc aaggtggtga tgctggtgga ggagtgccag tgcaaggtga agacggagca tgaagatgga cacatcctac atgctggctc ccaggattcc tttatcccag gagtttga. It is sometimes possible for the material contained within the vial of "CER1, cDNA Clone" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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