CCAR1 cdna clone
CCAR1 cDNA Clone
NCBI and Uniprot Product Information
Uniprot Description
CCAR1: Associates with components of the Mediator and p160 coactivator complexes that play a role as intermediaries transducing regulatory signals from upstream transcriptional activator proteins to basal transcription machinery at the core promoter. Recruited to endogenous nuclear receptor target genes in response to the appropriate hormone. Also functions as a p53 coactivator. May thus play an important role in transcriptional regulation. May be involved in apoptosis signaling in the presence of the reinoid CD437. Apoptosis induction involves sequestration of 14-3-3 protein(s) and mediated altered expression of multiple cell cycle regulatory genes including MYC, CCNB1 and CDKN1A. Plays a role in cell cycle progression and/or cell proliferation. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Apoptosis; RNA splicing; Nuclear receptor co-regulator
Chromosomal Location of Human Ortholog: 10q21.3
Cellular Component: nucleoplasm
Molecular Function: ligand-dependent nuclear receptor transcription coactivator activity; protein binding; transcription coactivator activity; transcription corepressor activity
Biological Process: nuclear mRNA splicing, via spliceosome; positive regulation of cell migration; positive regulation of cell proliferation
Research Articles on CCAR1
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Product Notes
The CCAR1 ccar1 (Catalog #AAA1273950) is a cDNA Clone and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: atggctcaat ttggaggaca gaagaatccg ccatgggcta ctcagtttac agccactgca gtatcacagc cagctgcact gggtgttcaa cagccatcac tccttggagc atctcctacc atttatacac agcaaactgc attggcagca gcaggcctta ccacacaaac tccagcaaac tatcagttaa cacaaactgc tgcattgcag caacaagccg cagctgcagc agctgcatta caacagcaat attcacaacc tcagcaggcc ctgtatagtg tgcaacaaca gttacagcaa ccccagcaaa ccctcttaac acagccagct gttgcactgc ctacaagcct tagcctgtct actcctcagc caacagcaca aataactgta tcatatccaa caccaaggtc cagtcaacag caaacccagc ctcagaagca gcgtgttttc acaggggtgg ttacaaaact acatgatacg tttggatttg tggatgaaga tgtattcttt cagcttagtg ctgtcaaagg gaaaaccccc caagtaggtg acagagtatt ggttgaagct acttataatc ctaatatgcc ttttaaatgg aatgcacaga gaattcaaac actaccaaat cagaatcagt cgcaaaccca gccattactg aagactcctc ctgctgtact tcagccaatt gcaccacaga caacatttgg tgttcagact cagccccagc cccagtcact gctgcaggca cagatttcag cagcttctat tacaccacta ttgcagactc aaccacagcc cttattacag cagcctcagc aaaaagctgg tttattgcag cctcctgttc gtatagtttc acagccacaa ccggcacgac gattagatcc cccatcccga ttttcaggaa gaaatgacag aggggatcaa gtgcctaaca gaaaagatga tcgaagtcgt gagagagaga gagaaagacg tagatcgaga gaaagatcac ctcagaggaa acgttcccgg gaaagatctc cacgaagaga gcgagagcga tcacctcgga gagttcgacg tgttgttcca cgttacacag ttcagttttc aaagttttct ttagattgtc ccagttgtga catgatggaa ctaaggcgcc gttatcaaaa tttgtatata cctagtgact tttttgatgc tcaatttaca tgggtggatg ctttcccttt gtcaagacca tttcagctgg gaaattactg caatttttat gtaatgcaca gagaagtaga gtccttagaa aaaaatatgg ccattcttga tccaccagat gctgaccact tatacagtgc aaaggtaatg ctgatggcta gccctagtat ggaagattta tatcataagt catgtgctct tgctgaggac ccacaagaac ttcgagatgg attccaacat cctgctagac ttgttaagtt tttagtgggc atgaaaggca aggatgaagc tatggccatt ggaggccact ggtctccttc gttggatgga ccagacccag aaaaagatcc ctctgtgttg attaagactg ctattcgttg ttgtaaggct ctgacaggca ttgatctaag tgtgtgcaca caatggtacc gttttgcaga gattcgctac catcgccctg aggagaccca caaggggcgt acagttccag ctcatgtgga gacagtggtt ttatttttcc cggatgtttg gcattgcctt cccacccgct cagagtggga aaccctctcc cgaggataca agcagcagct ggtcgagaag cttcagggtg aacgcaagga ggctgatgga gaacaggatg aagaagagaa ggatgatggt gaagctaaag aaatttctac acctacccat tggtctaaac ttgatccaaa gacaatgaag gtaaatgacc tccgaaaaga attagaaagt cgagctctta gttccaaagg attaaaatcc cagttaatag cccgattgac aaaacagctt aaagtagagg aacaaaaaga agaacagaag gagttagaga aatctgaaaa agaagaggat gaggatgatg ataggaaatc tgaagacgat aaagaggaag aagaaaggaa acgtcaagag gaaatagaac gccagcgtcg agaaagaaga tatattttgc ctgatgaacc ggccatcatt gtacatccaa attgggctgc aaaaagtggc aagtttgatt gtagcatcat gtctttgagt gtcctattgg actacagatt agaggataat aaagaacatt catttgaggt ttcattgttt gcggaacttt tcaacgaaat gcttcaaaga gattttggtg tccgtatata caaatcatta ctgtctcttc ctgagaaaga ggacaaaaaa gaaaaggata aaaaaagcaa aaaagatgag agaaaagata aaaaagaaga aagagatgat gaaactgatg aaccaaaacc caaacggaga aaatcaggcg atgataaaga taaaaaagaa gatagagatg aaaggaagaa agaagataaa agaaaagatg attctaaaga tgatgatgaa actgaagaag ataacaatca agatgaatat gaccctatgg aagcagaaga agctgaggat gaagaagatg atagggatga ggaagaaatg accaaacgag atgacaaaag agatatcaac agatactgca aggagaggcc ctctaaagat aaggaaaaag aaaagactca aatgatcaca attaacagag atctgttaat ggcttttgtt tattttgatc aaagtcattg tggttacctt cttgaaaagg atttggaaga aatactttat actcttggac tacatctttc tcgggctcag gtaaagaagc ttcttaataa agtagtgctc cgtgaatctt gcttttaccg gaaattaaca gacacctcaa aagatgaaga gaaccatgaa gagtctgagt cattgcagga agatatgcta ggaaacagat tattacttcc aacaccaaca gtaaagcagg aatcaaagga tgtggaagaa aatgttggcc tcattgtgta caatggtgca atggtagatg taggaagcct cttgcaaaaa ttggaaaaga gcgaaaaagt aagagctgag gtagaacaga agctgcagtt actagaagaa aaaacagatg aagatgaaaa aaccatatta aatttggaga attccaacaa aagcctctct ggtgaactca gagaagttaa aaaggacctt agtcagttac aagaaaactt aaagatttcg gaaaacatga atttacaatt tgaaaaccaa atgaataaga caatcagaaa cttatctacg gtaatggatg aaatccacac tgttctcaag aaggataatg taaagaatga agacaaagat caaaaatcca aggagaatgg tgccagtgta tga. It is sometimes possible for the material contained within the vial of "CCAR1, cDNA Clone" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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