ARL6IP1 cdna clone
ARL6IP1 cDNA Clone
NCBI and Uniprot Product Information
NCBI Description
This gene belongs to the ARL6ip family and encodes a transmembrane protein that is predominantly localized to intracytoplasmic membranes. It is highly expressed in early myeloid progenitor cells and thought to be involved in protein transport, membrane trafficking, or cell signaling during hematopoietic maturation. Mutations in this gene are associated with spastic paraplegia 61 (SPG61). Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Sep 2015]
Uniprot Description
ARL6IP: May be involved in protein transport, membrane trafficking, or cell signaling during hematopoietic maturation. Belongs to the ARL6ip family.
Protein type: Membrane protein, integral; Membrane protein, multi-pass
Chromosomal Location of Human Ortholog: 16p12-p11.2
Cellular Component: endoplasmic reticulum membrane; integral to endoplasmic reticulum membrane; integral to membrane; membrane; translocon complex
Molecular Function: protein binding
Biological Process: cotranslational protein targeting to membrane; negative regulation of apoptosis; negative regulation of caspase activity; positive regulation of L-glutamate transport
Disease: Spastic Paraplegia 61, Autosomal Recessive
Research Articles on ARL6IP1
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Product Notes
The ARL6IP1 arl6ip1 (Catalog #AAA1271086) is a cDNA Clone and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: atggcggagg gagataatcg cagcaccaac ctgctggctg cagagactgc aagtctggaa gaacagctgc aaggatgggg agaagtgatg ctgatggctg ataaagtcct ccgatgggaa agagcctggt ttccacctgc catcatgggt gtggtttctt tggtgtttct gattatctac tatctagatc catctgttct gtccggcgtt tcctgttttg ttatgttttt gtgcttggct gactaccttg ttcccattct agcgcctaga atttttggct ccaataaatg gaccactgaa caacagcaaa gattccatga aatttgcagc aatctagtaa aaactcgacg cagagctgtg ggttggtgga aacgcctctt cacactaaag gaagaaaaac ctaagatgta cttcatgacc atgatcgttt cccttgctgc ggttgcttgg gtgggacaac aagtccacaa cctgcttctc acctacctga tagtgacttc cttactattg cttcctggac taaaccaaca tggaatcatt ttgaagtaca ttggaatggc caagagggag ataaacaaac ttctcaaaca aaaagaaaag aaaaacgaat ga. It is sometimes possible for the material contained within the vial of "ARL6IP1, cDNA Clone" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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