AMHR2 cdna clone
AMHR2 cDNA Clone
NCBI and Uniprot Product Information
NCBI Description
This gene encodes the receptor for the anti-Mullerian hormone (AMH) which, in addition to testosterone, results in male sex differentiation. AMH and testosterone are produced in the testes by different cells and have different effects. Testosterone promotes the development of male genitalia while the binding of AMH to the encoded receptor prevents the development of the mullerian ducts into uterus and Fallopian tubes. Mutations in this gene are associated with persistent Mullerian duct syndrome type II. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Sep 2009]
Uniprot Description
MISR2: On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for anti-Muellerian hormone. Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.
Protein type: EC 2.7.11.30; Protein kinase, Ser/Thr (receptor); Protein kinase, TKL; Kinase, protein; Membrane protein, integral; TKL group; STKR family; Type2 subfamily
Chromosomal Location of Human Ortholog: 12q13
Molecular Function: hormone binding; protein binding; receptor activity
Biological Process: sex differentiation; signal transduction
Disease: Persistent Mullerian Duct Syndrome, Types I And Ii
Research Articles on AMHR2
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Product Notes
The AMHR2 amhr2 (Catalog #AAA1266199) is a cDNA Clone and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: atgctagggt ctttggggct ttgggcatta cttcccacag ctgtggaagc acccccaaac aggcgaacct gtgtgttctt tgaggcccct ggagtgcggg gaagcacaaa gacactggga gagctgctag atacaggcac agagctcccc agagctatcc gctgcctcta cagccgctgc tgctttggga tctggaacct gacccaagac cgggcacagg tggaaatgca aggatgccga gacagtgatg agccaggctg tgagtccctc cactgtgacc caagtccccg agcccacccc agccctggct ccactctctt cacctgctcc tgtggcactg acttctgcaa tgccaattac agccatctgc ctcctccagg gagccctggg actcctggct cccagggtcc ccaggctgcc ccaggtgagt ccatctggat ggcactggtg ctgctggggc tgttcctcct cctcctgctg ctgctgggca gcatcatctt ggccctgcta cagcgaaaga actacagagt gcgaggtgag ccagtgccag agccaaggcc agactcaggc agggactgga gtgtggagct gcaggagctg cctgagctgt gtttctccca ggtaatccgg gaaggaggtc atgcagtggt ttgggccggg cagctgcaag gaaaactggt tgccatcaag gccttcccac cgaggtctgt ggctcagttc caagctgaga gagcattgta cgaacttcca ggcctacagc acgaccacat tgtccgattt atcactgcca gccggggggg tcctggccgc ctgctctctg ggcccctgct ggtactggaa ctgcatccca agggctccct gtgccactac ttgacccagt acaccagtga ctggggaagt tccctgcgga tggcactgtc cctggcccag ggcctggcat ttctccatga ggagcgctgg cagaatggcc aatataaacc aggtattgcc caccgagatc tgagcagcca gaatgtgctc attcgggaag atggatcgtg tgccattgga gacctgggcc ttgccttggt gctccctggc ctcactcagc cccctgcctg gacccctact caaccacaag gcccagctgc catcatggaa gctggcaccc agaggtacat ggcaccagag ctcttggaca agactctgga cctacaggat tggggcatgg ccctccgacg agctgatatt tactctttgg ctctgctcct gtgggagata ctgagccgct gcccagattt gaggcctgac agcagtccac cacccttcca actggcctat gaggcagaac tgggcaatac ccctacctct gatgagctat gggccttggc agtgcaggag aggaggcgtc cctacatccc atccacctgg cgctgctttg ccacagaccc tgatgggctg agggagctcc tagaagactg ttgggatgca gacccagaag cacggctgac agctgagtgt gtacagcagc gcctggctgc cttggcccat cctcaagaga gccacccctt tccagagagc tgtccacgtg gctgcccacc tctctgccca gaagactgta cttcaattcc tgcccctacc atcctcccct gtaggcctca gcggagtgcc tgccacttca gcgttcagca aggcccttgt tccaggaatc ctcagcctgc ctgtaccctt tctcctgtgt aa. It is sometimes possible for the material contained within the vial of "AMHR2, cDNA Clone" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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