A2LD1 cdna clone
A2LD1 cDNA Clone
NCBI and Uniprot Product Information
NCBI Description
The protein encoded by this gene aids in the proteolytic degradation of crosslinked fibrin by breaking down isodipeptide L-gamma-glutamyl-L-epsilon-lysine, a byproduct of fibrin degradation. The reaction catalyzed by the encoded gamma-glutamylaminecyclotransferase produces 5-oxo-L-proline and a free alkylamine. Two transcript variants encoding the same protein have been found for this gene.[provided by RefSeq, Aug 2010]
Uniprot Description
A2LD1: Contributes to degradation of proteins cross-linked by transglutaminases. Degrades the cross-link between a lysine and a glutamic acid residue from two proteins that have been cross- linked by transglutaminases. Catalyzes the formation of 5- oxoproline from L-gamma-glutamyl-L-epsilon-lysine. Inactive with L-gamma-glutamyl-alpha-amino acid substrates such as L-gamma- glutamyl-L-alpha-cysteine and L-gamma-glutamyl-L-alpha-alanine. Belongs to the gamma-glutamylcyclotransferase family.
Protein type: EC 2.3.2.4; Transferase
Chromosomal Location of Human Ortholog: 13q32.3
Molecular Function: gamma-glutamylcyclotransferase activity; protein binding
Biological Process: amino acid derivative catabolic process
Research Articles on A2LD1
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Product Notes
The A2LD1 ggact (Catalog #AAA1278394) is a cDNA Clone and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: atggccctag tcttcgtgta cggcaccctg aagcggggtc agcccaacca cagggtcctg cgggacggcg cccacggctc cgcagccttt cgggcgcgcg gccgcacgct ggagccctac ccgttggtga tcgcggggga gcacaacatc ccgtggctgc tgcacctgcc cggctcgggg cgcctcgtgg agggcgaggt ctacgcggta gacgagcgga tgctgcgctt tctggatgac ttcgagagtt gcccggccct gtaccagcgc acggtgctgc gggtacagct gctggaggac cgggccccgg gcgcagagga gccgccagcg cccaccgcgg tgcagtgctt cgtgtacagc agggccacct tcccgccgga gtgggcccag ctcccgcacc atgacagcta cgactccgag gggccgcacg ggctgcgcta caacccccgg gagaacagat aa. It is sometimes possible for the material contained within the vial of "A2LD1, cDNA Clone" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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