CDKL2 recombinant protein
Recombinant Human CDKL2 Protein (His tag)
Gene Names
CDKL2; P56; KKIAMRE
Purity
> 85 % as determined by SDS-PAGE
Synonyms
CDKL2; Recombinant Human CDKL2 Protein (His tag); KKIAMRE; P56; CDKL2 recombinant protein
Host
Baculovirus-Insect Cells
Purity/Purification
> 85 % as determined by SDS-PAGE
Form/Format
Supplied as sterile 20mM Tris, 500mM NaCl, pH 7.4, 10% gly
Sequence Length
570
Application Notes
The recombinant human CDKL2 consists of 512 amino acids and has a calculated molecular mass of 58.3 kDa. It migrates as an approximately 63 kDa band in SDS-PAGE under reducing conditions as predicted.
Predicted N Terminal
Met
Endotoxin
< 1.0 EU per mug of the protein as determined by the LAL method
Preparation and Storage
Samples are stable for up to twelve months from date of receipt at -70 degree C
Related Product Information for CDKL2 recombinant protein
Background: Cyclin-dependent kinase-like 2 (Cdkl2) is a member of cdc2-related serine / threonine protein kinase family and it is found expressed in various brain regions, including the cerebral cortex, entorinal cortex, hippocampus, amygdala, and dorsal thalamus. The high expression in these brain regions suggests that Cdkl2 may have functions in congnition and emotion processes. Cdkl2 accumulates primarily in the cytoplasm, with lower levels in the nucleus.
Description: A DNA sequence encoding the human CDKL2 (Q92772) (Met 1-His 493) was expressed, with a polyhistidine tag at the N-terminus.
Description: A DNA sequence encoding the human CDKL2 (Q92772) (Met 1-His 493) was expressed, with a polyhistidine tag at the N-terminus.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
56,019 Da
NCBI Official Full Name
cyclin-dependent kinase-like 2 isoform 2
NCBI Official Synonym Full Names
cyclin dependent kinase like 2
NCBI Official Symbol
CDKL2
NCBI Official Synonym Symbols
P56; KKIAMRE
NCBI Protein Information
cyclin-dependent kinase-like 2
UniProt Protein Name
Cyclin-dependent kinase-like 2
Protein Family
UniProt Gene Name
CDKL2
NCBI Description
This gene product is a member of a large family of CDC2-related serine/threonine protein kinases. It accumulates primarily in the cytoplasm, with lower levels in the nucleus. [provided by RefSeq, Jul 2008]
Uniprot Description
CDKL2: a protein kinase of the CDKL family. Accumulates primarily in the cytoplasm, with a lower level in the nucleus.
Protein type: CDKL family; CMGC group; Cell cycle regulation; EC 2.7.11.22; Kinase, protein; Protein kinase, CMGC; Protein kinase, Ser/Thr (non-receptor)
Chromosomal Location of Human Ortholog: 4q21.1
Cellular Component: centrosome; nucleus
Molecular Function: protein kinase activity
Biological Process: sex differentiation; signal transduction
Research Articles on CDKL2
Similar Products
Product Notes
The CDKL2 cdkl2 (Catalog #AAA2545071) is a Recombinant Protein produced from Baculovirus-Insect Cells and is intended for research purposes only. The product is available for immediate purchase. The recombinant human CDKL2 consists of 512 amino acids and has a calculated molecular mass of 58.3 kDa. It migrates as an approximately 63 kDa band in SDS-PAGE under reducing conditions as predicted. Researchers should empirically determine the suitability of the CDKL2 cdkl2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CDKL2, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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