Cdk2/Cycliny Peptide I, Inhibitor | Cdk2/CyclinyI, inhibitor

Cdk2/Cyclin Inhibitory Peptide I

Cat. Num. AAA5764159

• Purity: 98.00%
• Synonyms: Cdk2/Cycliny Peptide I; Cdk2/Cyclin Inhibitory Peptide I; Cdk2/CyclinyI; inhibitor

• Purity/Purification: 98.00%
• Form/Format: Solid. Powder

• Solubility: DMSO: >=257.1mg/mL; DMSO: >=257.1mg/mL; (<1mg/ml refers to the product slightly soluble or insoluble)
• Formula: C111H196N48O23
• SMILES: N[C@@]([H])(C/C1=C/C=C(/O)C=C1)C(=O)NCC(=O)N[C@]([H])(CCCNC(N)=N)C(=O)N[C@]([H])(CCCCN)C(=O)N[C@]([H])(CCCCN)C(=O)N[C@]([H])(CCCNC(N)=N)C(=O)N[C@]([H])(CCCNC(N)=N)C(=O)N[C@]([H])(CCC(N)=O)C(=O)N[C@]([H])(CCCNC(N)=N)C(=O)N[C@]([H])(CCCNC(N)=N)C(=O)N[C@]([H])(CCCNC(N)=N)C(=O)NCC(=O)N2CCC[C@]2([H])C(=O)N[C@@]([H])(C(=O)N[C@]([H])(CCCCN)C(=O)N[C@]([H])(CCCNC(N)=N)C(=O)N[C@]([H])(CCCNC(N)=N)C(=O)N[C@]([H])(CC(C)(C)[H])C(=O)N[C@]([H])(C/C3=C/C=CC=C3)C(=O)NCC(O)=O)C(C)(C)[H]
• In Vitro: It is a catalytic subunit of the cyclin-dependent kinase complex, whose activity is restricted to the G1-S phase of the cell cycle and is essential for the G1/S transition. This protein associate with and is regulated by the regulatory subunits of the complex including cyclin E or A. Cyclin E binds G1 phase Cdk2, which is required for the transition from G1 to S phase while binding with Cyclin A is required to progress through the S phase. Its activity is also regulated by phosphorylation. Two alternatively spliced variants and multiple transcription initiation sites of this gene have been reported. The role of this protein in the G1-S transition has been recently questioned as cells lacking Cdk2 are reported to have no problem during this transition [2][3].
• Preparation and Storage: Store at -20 degree C for 3 years powder; -80 degree C for 2 years in solvent

Related Product Information for Cdk2/CyclinyI, inhibitor

Cyclin-dependent kinase 2 also known as cell division protein kinase 2. The protein encoded by this gene is a member of the cyclin-dependent kinase family of Ser/Thr protein kinases. This protein kinase is highly similar to the gene products of S. cerevisiae cdc28, and S. pombe cdc2, also known as Cdk1 in humans.