CDH11 recombinant protein

CDH11, 54-617aa, Human, His tag, E Coli

Cat. Num. AAA205348

• Gene Names: CDH11; OB; CAD11; CDHOB; OSF-4
• Applications: SDS-Page
• Purity: > 85% by SDS-PAGE
• Synonyms: CDH11; 54-617aa; Human; His tag; E Coli; Cadherin 11 type 2; Cadherin 11; type 2; CAD11; CDHOB; OB; OSF-4; CDH11 recombinant protein

• Host: E Coli
• Purity/Purification: > 85% by SDS-PAGE
• Form/Format: Liquid. 20mM Tris-HCl Buffer (pH 8.0) containing 10% glycerol 0.1M NaCl
• Concentration: 1 mg/ml (determined by Bradford assay) (varies by lot)
• Sequence: MRGSHHHHHH GMASMTGGQQ MGRDLYDDDD KDRWGSMGWV WNQFFVIEEY TGPDPVLVGR LHSDIDSGDG NIKYILSGEG AGTIFVIDDK SGNIHATKTL DREERAQYTL MAQAVDRDTN RPLEPPSEFI VKVQDINDNP PEFLHETYHA NVPERSNVGT SVIQVTASDA DDPTYGNSAK LVYSILEGQP YFSVEAQTGI IRTALPNMDR EAKEEYHVVI QAKDMGGHMG GLSGTTKVMI TLTDVNDNPP KFPQSVYQMS VSEAAVPGEE VGRVKAKDPD IGENGLVTYN IVDGDGMESF EITTDYETQE GVIKLKKPVD FETKRAYSLK VEAANVHIDP KFISNGPFKD TVTVKIAVED ADEPPMFLAP SYIHEVQENA AAGTVVGRVH AKDPDAANSP IRYSIDRHTD LDRFFTINPE DGFIKTTKPL DREETAWLNI TVFAAEIHNR HQEAKVPVAI RVLDVNDNAP KFAAPYEGFI CESDQTKPLS NQPIVTISAD DKDDTANGPR FIFSLPPEII HNPNFTVRDN RDNTAGVYAR RGGFSRQKQD LYLLPIVISD GGIPPMSSTN TLTIKVCGCD VNGALLSCNA EAYILNAGLS T
• Sequence Length: 796

• Applicable Applications for CDH11 recombinant protein: SDS-PAGE
• Antigen Species: Human
• Tag Information: His-tag
• Preparation and Storage: Can be stored at 4 degree C short term (1-2 weeks).; For long term storage, aliquot and store at -20 degree C or -70 degree C.; Avoid repeated freezing and thawing cycles.

SDS-Page

Related Product Information for CDH11 recombinant protein

CDH11, also known as cadherin 11, is a member of the cadherin superfamily, integral membrane proteins that mediate calcium-dependent cell-cell adhesion. This protein is defined based on their lack of a HAV cell adhesion recognition sequence specific to type I cadherins. Expression of this particular cadherin in osteoblastic cell lines, and its upregulation during differentiation, suggests a specific function in bone development and maintenance. Recombinant human CDH11 protein, fused to His-tag at N-terminus, was expressed in E Coli and purified by using conventional chromatography techniques.

Product Categories/Family for CDH11 recombinant protein

Cancer

References

Pishvaian MJ. et al. (1999) Cancer Res. 59:947-952.; Suzuki S. et al. (1991) Cell Regul. 2:261-270.;

NCBI and Uniprot Product Information

• NCBI GI #: 15488966
• NCBI GeneID: 1009
• Molecular Weight: 66.2 kDa (601aa)
• NCBI Official Full Name: Cadherin 11, type 2, OB-cadherin (osteoblast)
• NCBI Official Synonym Full Names: cadherin 11
• NCBI Official Symbol: CDH11
• NCBI Official Synonym Symbols: OB; CAD11; CDHOB; OSF-4
• NCBI Protein Information: cadherin-11
• UniProt Protein Name: Cadherin-11
• Protein Family: Cadherin
• UniProt Gene Name: CDH11
• UniProt Synonym Gene Names: OB-cadherin

NCBI Description

This gene encodes a type II classical cadherin from the cadherin superfamily, integral membrane proteins that mediate calcium-dependent cell-cell adhesion. Mature cadherin proteins are composed of a large N-terminal extracellular domain, a single membrane-spanning domain, and a small, highly conserved C-terminal cytoplasmic domain. Type II (atypical) cadherins are defined based on their lack of a HAV cell adhesion recognition sequence specific to type I cadherins. Expression of this particular cadherin in osteoblastic cell lines, and its upregulation during differentiation, suggests a specific function in bone development and maintenance. [provided by RefSeq, Jul 2008]

Uniprot Description

Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types.