Cell division control protein 12 (CDC12) Recombinant Protein | CDC12 recombinant protein
Recombinant Saccharomyces cerevisiae Cell division control protein 12 (CDC12)
NCBI and Uniprot Product Information
Uniprot Description
Septins are GTPases involved in cytokinesis that assemble early in the cell cycle as a patch at the incipient bud site and form a ring approximate 15 minutes before bud emergence, which transforms into an hour-glass shaped collar of cortical filaments that spans both sides of the mother-bud neck. This collar persists until just before cytokinesis, when it splits into two rings that occupy opposite sides of the neck. The septins at the bud neck serve as a structural scaffold that recruits different components involved in diverse processes at specific stages during the cell cycle. Many proteins bind asymmetrically to the septin collar. The septin assembly is regulated by protein kinases GIN4 and/or CLA4. May act by recruiting MYO1 and HOF1, a protein involved in septation, to the site of cleavage. Septins are also involved in cell morphogenesis, bud site selection, chitin deposition, cell cycle regulation, cell compartmentalization and spore wall formation.Miscellaneous: Present with 1170 molecules/cell in log phase SD medium.
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Product Notes
The CDC12 cdc12 (Catalog #AAA1210158) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 2-407, full length protein. The amino acid sequence is listed below: SAATATAAPV PPPVGISNLP NQRYKIVNEE GGTFTVMLCG ESGLGKTTFI NTLFQTVLKR ADGQQHRQEP IRKTVEIDIT RALLEEKHFE LRVNVIDTPG FGDNVNNNKA WQPLVDFIDD QHDSYMRQEQ QPYRTKKFDL RVHAVLYFIR PTGHGLKPID IETMKRLSTR ANLIPVIAKA DTLTAQELQQ FKSRIRQVIE AQEIRIFTPP LDADSKEDAK SGSNPDSAAV EHARQLIEAM PFAIVGSEKK FDNGQGTQVV ARKYPWGLVE IENDSHCDFR KLRALLLRTY LLDLISTTQE MHYETYRRLR LEGHENTGEG NEDFTLPAIA PARKLSHNPR YKEEENALKK YFTDQVKAEE QRFRQWEQNI VNERIRLNGD LEEIQGKVKK LEEQVKSLQV KKSHLK. It is sometimes possible for the material contained within the vial of "Cell division control protein 12 (CDC12), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
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