Leukocyte surface antigen CD47 (Cd47) Recombinant Protein | Cd47 recombinant protein
Recombinant Rat Leukocyte surface antigen CD47 (Cd47)
NCBI and Uniprot Product Information
NCBI Description
protein that may be involved in regulating renal cell growth; overexpression is associated with Fe-NTA-induced renal damage and tumor progression and metastasis [RGD, Feb 2006]
Uniprot Description
CD47: Has a role in both cell adhesion by acting as an adhesion receptor for THBS1 on platelets, and in the modulation of integrins. Plays an important role in memory formation and synaptic plasticity in the hippocampus. Receptor for SIRPA, binding to which prevents maturation of immature dendritic cells and inhibits cytokine production by mature dendritic cells. Interaction with SIRPG mediates cell-cell adhesion, enhances superantigen-dependent T-cell-mediated proliferation and costimulates T-cell activation. May play a role in membrane transport and/or integrin dependent signal transduction. May prevent premature elimination of red blood cells. May be involved in membrane permeability changes induced following virus infection. 4 isoforms of the human protein are produced by alternative splicing.
Protein type: Membrane protein, integral; Membrane protein, multi-pass; Motility/polarity/chemotaxis
Cellular Component: integral to plasma membrane; integral to membrane; plasma membrane
Biological Process: integrin-mediated signaling pathway; cell migration; response to bacterium; positive regulation of phagocytosis; positive regulation of cell proliferation; positive regulation of cell-cell adhesion; opsonization; positive regulation of T cell activation; cell adhesion; positive regulation of inflammatory response
Research Articles on Cd47
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Product Notes
The Cd47 cd47 (Catalog #AAA951943) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 19-303. The amino acid sequence is listed below: QLLLSKVKSV EFTSCNDTVV IPCKVLNVEA QSTDEMFVKW KLNKSYIFIY DGNKNSTTRE QNFTSAKISV SDLLKGIASL TMDTHEAVVG NYTCEVTELS REGKTVIELK NRPVSWFSTN EKILIVIFPI LAILLFWGKF GILTLKYKSS HTNKRIILLL VAGLALTLIV VVGAILFIPG EKPVKNASGL GLIVISTGIL ILLQYNVFMT AFGMTSFTIA ILITQVLGYV LAVVGMCLCI MACEPVHGPL LISGLGIIAL AELLGLVYMK FVASNQRTIQ PPRNN. It is sometimes possible for the material contained within the vial of "Leukocyte surface antigen CD47 (Cd47), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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