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CD62L Recombinant Protein | CD44 recombinant protein

CD62L, Recombinant, Human (L-Selectin, Leukocyte Endothelial Cell Adhesion Molecule-1, LECAM-1)

Purity
Highly Purified
95% (SDS-PAGE). Single band on Western Blot.
Synonyms
CD62L; Recombinant; Human (L-Selectin; Leukocyte Endothelial Cell Adhesion Molecule-1; LECAM-1); CD44 recombinant protein
Ordering
For Research Use Only!
Host
E Coli
Purity/Purification
Highly Purified
95% (SDS-PAGE). Single band on Western Blot.
Form/Format
Supplied as a liquid in 1X Laemmli Buffer (25mM Tris-HCl, pH 6.8, 50mM DTT, 1% SDS, 0.1% Bromophenol Blue and 2.5% glycerol).
Application Notes
Recombinant Human L-Selectin can be used directly as a positive control in Western blotting, ELISA, immunoprecipitation and other immunological experiments. The biological activity of this product has not yet been tested.
Preparation and Storage
-20 degree C
Stability: Store at 4 degree C if entire vial will be used within 1-2 weeks. Store, frozen at -20 degree C for longer periods of time. Please avoid freeze-thaw cycles.
Related Product Information for CD44 recombinant protein
L-Selectin belongs to a family of divalent cation-dependent carbohydrate-binding glycoproteins or adhesion molecules. Lselectin is expressed constitutively on lymphocytes, monocytes and granulocytes and interacts specifically with carbohydrate groups on activated endothelial cells. L-Selectin may be shed by proteolytic cleavage and circulating levels in biological fluids may be used as an indicator of various pathological conditions. Recombinant Human L-Selectin is expressed in E. coli containing 294 amino acids 39-332 fused to an amino terminal hexahistidine tag.
Product Categories/Family for CD44 recombinant protein

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
40,002 Da
NCBI Official Full Name
CD44 antigen
NCBI Official Symbol
CD44
NCBI Protein Information
CD44 antigen; PGP-1; PGP-I; HUTCH-I; ECMR-III; hermes antigen; hyaluronate receptor; phagocytic glycoprotein 1; phagocytic glycoprotein I; extracellular matrix receptor III; GP90 lymphocyte homing/adhesion receptor; homing function and Indian blood group system
UniProt Protein Name
CD44 antigen
Protein Family
UniProt Gene Name
CD44
UniProt Synonym Gene Names
ECMR-III; PGP-1; PGP-I
UniProt Entry Name
CD44_BOVIN

Uniprot Description

Function: Main cell surface receptor for hyaluronate. Adhesion to mucosal high endothelial venule and to types I and VI collagen. Probably involved in matrix adhesion, lymphocyte activation and lymph node homing. May play an important role in invadopodia formation

By similarity.

Subunit structure: Interacts with PKN2

By similarity.

Subcellular location: Membrane; Single-pass type I membrane protein. Note: Colocalizes with actin in membrane protrusions at wounding edges

By similarity.

Tissue specificity: Mesenteric lymph node and liver, not in heart.

Domain: The lectin-like LINK domain is responsible for hyaluronan binding

By similarity.

Post-translational modification: N- and O-glycosylated; contains glycosaminoglycan chondroitin sulfate

By similarity.Phosphorylated on serine residues

By similarity.

Sequence similarities: Contains 1 Link domain.

Research Articles on CD44

Similar Products

Product Notes

The CD44 cd44 (Catalog #AAA636290) is a Recombinant Protein produced from E Coli and is intended for research purposes only. The product is available for immediate purchase. Recombinant Human L-Selectin can be used directly as a positive control in Western blotting, ELISA, immunoprecipitation and other immunological experiments. The biological activity of this product has not yet been tested. Researchers should empirically determine the suitability of the CD44 cd44 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CD62L, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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