Cat Cluster of Differentiation 109 ELISA Kit | CD109 elisa kit

Cat Cluster of Differentiation 109 ELISA Kit

Cat. Num. AAA49291

• Gene Names: CD109; CPAMD7; RP11-525G3.1
• Reactivity: Cat
• Synonyms: Cluster of Differentiation 109; Cat Cluster of Differentiation 109 ELISA Kit; CD109 elisa kit

• Reactivity: Cat

• Samples: Mouse Body Fluids And Tissue Homogenates
• Assay Type: Quantitative Sandwich
• Detection Range: 15.6pg/ml-500pg/ml
• Sensitivity: 2.0pg/ml.
• Intra-assay Precision: Intra-assay CV (%) is less than 15%
• Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100]. All CV% should be compared by concentration, not compared by OD values.
• Preparation and Storage: Store all reagents at 2-8 degree C

Related Product Information for CD109 elisa kit

Background/Introduction: This Quantitative Sandwich ELISA kit is for lab reagent/research use only! This kit is intended to be used for determine the level of CCTGF (hereafter termed "analyte") in undiluted original Mouse body fluids and tissue homogenates. This kit is NOT suitable for assaying non-biological sources of substances.

NCBI and Uniprot Product Information

• NCBI GI #: 227430303
• NCBI GeneID: 135228
• NCBI Accession #: NP_001153060.1
• NCBI GenBank Nucleotide #: NM_001159588.1
• UniProt Accession #: Q6YHK3; Q0P6K7; Q5SYA8; Q5XUM7; Q5XUM9; Q6MZI7; Q8N3A7; Q8N915; Q8TDJ2; A5YKK4; B2R948; B3KW25
• Molecular Weight: 161,689 Da
• NCBI Official Full Name: CD109 antigen isoform 3
• NCBI Official Synonym Full Names: CD109 molecule
• NCBI Official Symbol: CD109
• NCBI Official Synonym Symbols: CPAMD7; RP11-525G3.1
• NCBI Protein Information: CD109 antigen; p180; r150; Gov platelet alloantigens; activated T-cell marker CD109; platelet-specific Gov antigen; 150 kDa TGF-beta-1-binding protein; C3 and PZP-like alpha-2-macroglobulin domain-containing protein 7
• UniProt Protein Name: CD109 antigen
• Protein Family: CD109 antigen
• UniProt Gene Name: CD109
• UniProt Synonym Gene Names: CPAMD7
• UniProt Entry Name: CD109_HUMAN

NCBI Description

This gene encodes a member of the alpha2-macroglobulin/complement superfamily. The encoded GPI-linked glycoprotein is found on the cell surface of platelets, activated T-cells, and endothelial cells. The protein binds to and negatively regulates signaling of transforming growth factor beta (TGF-beta). Multiple transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Apr 2009]

Uniprot Description

CD109: Modulates negatively TGFB1 signaling in keratinocytes. Belongs to the protease inhibitor I39 (alpha-2- macroglobulin) family. 4 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, GPI anchor

Chromosomal Location of Human Ortholog: 6q13

Cellular Component: extracellular space; cell surface; plasma membrane

Molecular Function: serine-type endopeptidase inhibitor activity; transforming growth factor beta binding

Biological Process: negative regulation of protein amino acid phosphorylation; hair follicle development; negative regulation of transforming growth factor beta receptor signaling pathway; regulation of keratinocyte differentiation