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Immunohistochemistry (IHC) (Peptide-+ Immunohistochemical analysis of paraffin-embedded human lung carcinoma tissue using Cyclin G antibody.)

Cyclin G Antibody | anti-CCNG antibody

Cyclin G Antibody

Gene Names
CCNG1; CCNG
Reactivity
Human, Mouse, Rat
Applications
Western Blot, Immunohistochemistry, ELISA
Purity
Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Synonyms
Cyclin G; Cyclin G Antibody; Ribosomal protein S6 kinase I; S6K; S6K1; 70 kDa ribosomal protein S6 kinase 1; p70 S6 kinase alpha; p70(S6K)-alpha; p70-S6K; P70S6K; p70-alpha; anti-CCNG antibody
Ordering
For Research Use Only!
Reactivity
Human, Mouse, Rat
Specificity
Cyclin G antibody detects endogenous levels of total Cyclin G protein.
Purity/Purification
Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Form/Format
In phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Sequence Length
295
Applicable Applications for anti-CCNG antibody
Western Blot (WB), Immunohistochemistry (IHC), ELISA (EIA)
Application Notes
WB: 1:500~1:1000
IHC: 1:50~1:100
ELISA: 1:40000
Immunogen
The antiserum was produced against synthesized peptide derived from human Cyclin G.
Preparation and Storage
Store at-20 degree C for 1 year

Immunohistochemistry (IHC)

(Peptide-+ Immunohistochemical analysis of paraffin-embedded human lung carcinoma tissue using Cyclin G antibody.)

Immunohistochemistry (IHC) (Peptide-+ Immunohistochemical analysis of paraffin-embedded human lung carcinoma tissue using Cyclin G antibody.)

Western Blot (WB)

(Western blot analysis of extracts from Jurkat cells, using Cyclin G antibody.)

Western Blot (WB) (Western blot analysis of extracts from Jurkat cells, using Cyclin G antibody.)
References
Philip J. Papst, et al. (1998) J. Biol. Chem; 273: 15077. Satoru Eguchi, et al. (999) J. Biol. Chem 1; 274: 36843. Ana González-García, et al. (2002) J. Biol. Chem; 277: 1500-1508. Ulrike Krause, et al. (2002) Eur. J. Biochem; 269: 3751.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
900
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
18,769 Da
NCBI Official Full Name
cyclin-G1
NCBI Official Synonym Full Names
cyclin G1
NCBI Official Symbol
CCNG1
NCBI Official Synonym Symbols
CCNG
NCBI Protein Information
cyclin-G1
UniProt Protein Name
Cyclin-G1
Protein Family
UniProt Gene Name
CCNG1
UniProt Synonym Gene Names
CCNG; CYCG1; Cyclin-G

NCBI Description

The eukaryotic cell cycle is governed by cyclin-dependent protein kinases (CDKs) whose activities are regulated by cyclins and CDK inhibitors. The protein encoded by this gene is a member of the cyclin family and contains the cyclin box. The encoded protein lacks the protein destabilizing (PEST) sequence that is present in other family members. Transcriptional activation of this gene can be induced by tumor protein p53. Two transcript variants encoding the same protein have been identified for this gene. [provided by RefSeq, Jul 2008]

Uniprot Description

May play a role in growth regulation. Is associated with G2/M phase arrest in response to DNA damage. May be an intermediate by which p53 mediates its role as an inhibitor of cellular proliferation ().

Research Articles on CCNG

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Product Notes

The CCNG ccng1 (Catalog #AAA853554) is an Antibody and is intended for research purposes only. The product is available for immediate purchase. The Cyclin G Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's Cyclin G can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC), ELISA (EIA). WB: 1:500~1:1000 IHC: 1:50~1:100 ELISA: 1:40000. Researchers should empirically determine the suitability of the CCNG ccng1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Cyclin G, Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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