Malcavernin (ccm2) Recombinant Protein | ccm2 recombinant protein
Recombinant Danio rerio Malcavernin (ccm2)
Gene Names
ccm2; vtn; TUF2; zgc:110233
Purity
Greater or equal to 85% purity as determined by SDS-PAGE.
Synonyms
Malcavernin (ccm2); Recombinant Danio rerio Malcavernin (ccm2); ccm2 recombinant protein
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE.
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Sequence Positions
1-455, Full length protein
Sequence
MEEDVKKVKKPGIVSPFKRVFLKGEKGRDKKALEKSTERRALHTFSLSLPDHRIDPDILLNDYIEKEVKYLGQLTSVPGYLNPSSRTEVLQLIDNARKSHQLAGQLTSEQDAVVSLSAYNVKLVWRDGEDIILRVPIHDIAAVSYIRDDSLHLVVLKTAQEPGGSPCHSTEMSKSPTLSSLSESGAVLVEVCCLLVLAVDNKAAAEELCLLLSQVFQIVYTESTIDFLDRAIFDGATTPTRHLSIYSEDSSSKVDVKDVFEAEASTFSFQSSLEAGHSSSPSPTSAPASPQTKTASESELSTTAAELLQDYMTTLRTKLSSKEIQQFATLLHEYRNGASIHEFCINLRQLYGDSRKFLLLGLRPFIPEKDSQHFENFLETIGVKDGRGIITDSFGRYKRTTSSASDSTTNGNGAAGGSDEGTATSEGDEWDRMISDISNDIEALGSSMDQDGVPS
Sequence Length
455
Species
Zebrafish
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
39,839 Da
NCBI Official Full Name
cerebral cavernous malformations protein 2 homolog
NCBI Official Synonym Full Names
cerebral cavernous malformation 2
NCBI Official Symbol
ccm2
NCBI Official Synonym Symbols
vtn; TUF2; zgc:110233
NCBI Protein Information
cerebral cavernous malformations protein 2 homolog
UniProt Protein Name
Cerebral cavernous malformations protein 2 homolog
Protein Family
UniProt Gene Name
ccm2
UniProt Synonym Gene Names
vtn
Uniprot Description
Component of the CCM signaling pathway which is a crucial regulator of heart and vessel formation and integrity. May act through the stabilization of endothelial cell junctions. May also function as a scaffold protein for MAP2K3-MAP3K3 signaling. Seems to play a major role in the modulation of MAP3K3-dependent p38 activation induced by hyperosmotic shock ().
Research Articles on ccm2
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Product Notes
The ccm2 ccm2 (Catalog #AAA1372057) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 1-455, Full length protein. The amino acid sequence is listed below: MEEDVKKVKK PGIVSPFKRV FLKGEKGRDK KALEKSTERR ALHTFSLSLP DHRIDPDILL NDYIEKEVKY LGQLTSVPGY LNPSSRTEVL QLIDNARKSH QLAGQLTSEQ DAVVSLSAYN VKLVWRDGED IILRVPIHDI AAVSYIRDDS LHLVVLKTAQ EPGGSPCHST EMSKSPTLSS LSESGAVLVE VCCLLVLAVD NKAAAEELCL LLSQVFQIVY TESTIDFLDR AIFDGATTPT RHLSIYSEDS SSKVDVKDVF EAEASTFSFQ SSLEAGHSSS PSPTSAPASP QTKTASESEL STTAAELLQD YMTTLRTKLS SKEIQQFATL LHEYRNGASI HEFCINLRQL YGDSRKFLLL GLRPFIPEKD SQHFENFLET IGVKDGRGII TDSFGRYKRT TSSASDSTTN GNGAAGGSDE GTATSEGDEW DRMISDISND IEALGSSMDQ DGVPS. It is sometimes possible for the material contained within the vial of "Malcavernin (ccm2), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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