Cathelicidin-BF antimicrobial peptide Recombinant Protein
Recombinant Bungarus fasciatus Cathelicidin-BF antimicrobial peptide
NCBI and Uniprot Product Information
Uniprot Description
Function: Potent antimicrobial peptide against most of Gram-negative bacteria, some Gram-positive bacteria (Bacillus) and some fungi (C.albicans, P.pastoris, A.terreus, A.nidulans, and C.globosum). Adopts an amphipathic alpha helical conformation, that may allow to partition into the target membrane. No hemolytic and cytotoxic activities have been observed on mammalian cells. Ref.1
Subcellular location: Secreted. Target cell membrane
Probable Ref.1.
Tissue specificity: Expressed by the venom gland, stomach, trachea, skin, muscle, heart, kidney, lung, brain, intestine, spleen, liver, and ovary. Ref.1
Miscellaneous: A predicted cleavage site is located at position Val-157-158-Lys, giving a peptide of 34 residues instead of the 30 residues found for the purified protein. The 30 residues cathelicidin-BF could result from a further processing.
Sequence similarities: Belongs to the cathelicidin family.
Mass spectrometry: Molecular mass is 3638.0±0.5 Da from positions 162 - 191. Determined by ESI. Ref.1
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Product Notes
The Cathelicidin-BF antimicrobial peptide (Catalog #AAA1114563) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 162-191aa; Full Length of Mature Protein. The amino acid sequence is listed below: KFFRKLKKSV KKRAKEFFKK PRVIGVSIPF. It is sometimes possible for the material contained within the vial of "Cathelicidin-BF antimicrobial peptide, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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