Testing Data
(Image: Mixed neuron-glial cultures stained with ACIII (red) and to aII-spectrin (green). Note the strong and clean staining of neuronal cilia. Since aII-spectrin is specific for neurons in the CNS, the glial cells in this culture are not recognized by this antibody. The aII-spectrin antibody is also an excellent marker of neuronal plasma membranes. Protocol on data-sheet.)
Adenylate Cyclase III/ADCY3 Antibody | anti-ADCY3 antibody
Adenylate Cyclase III/ADCY3, Antiserum, Rabbit
Testing Data
(Image: Mixed neuron-glial cultures stained with ACIII (red) and to aII-spectrin (green). Note the strong and clean staining of neuronal cilia. Since aII-spectrin is specific for neurons in the CNS, the glial cells in this culture are not recognized by this antibody. The aII-spectrin antibody is also an excellent marker of neuronal plasma membranes. Protocol on data-sheet.)
Testing Data
(Image: Mixed neuron-glial cultures stained with ACIII (red) and to aII-spectrin (green). Note the strong and clean staining of neuronal cilia. Since aII-spectrin is specific for neurons in the CNS, the glial cells in this culture are not recognized by this antibody. The aII-spectrin antibody is also an excellent marker of neuronal plasma membranes. Protocol on data-sheet.)
Testing Data
(Image: Western blots of rat olfactory epithelium (OE) and frontal cortex (FC). ACIII stains bands at about 200kDa in olfactory epithelium which is rich in cilia. Fewer cilia are found in frontal cortex, and the protein is less heavily glycosylated, and a less prominent band is seen at about 160kDa.Courtesy of Matt Sarkinsen. University of Florida. Protocol on data-sheet.)
Testing Data
(Image: Western blots of rat olfactory epithelium (OE) and frontal cortex (FC). ACIII stains bands at about 200kDa in olfactory epithelium which is rich in cilia. Fewer cilia are found in frontal cortex, and the protein is less heavily glycosylated, and a less prominent band is seen at about 160kDa.Courtesy of Matt Sarkinsen. University of Florida. Protocol on data-sheet.)
NCBI and Uniprot Product Information
Uniprot Description
ADCY3: a membrane-associated enzyme that catalyzes the formation of the secondary messenger cyclic adenosine monophosphate (cAMP). Widely expressed in various human tissues and may be involved in a number of physiological and pathophysiological metabolic processes. Involved in odorant detection (possibly) via modulation of intracellular cAMP concentration.
Protein type: Adenylyl cyclase; EC 4.6.1.1; Lyase; Membrane protein, integral; Membrane protein, multi-pass; Nucleotide Metabolism - purine; Transporter; Transporter, aquaporin family
Chromosomal Location of Human Ortholog: 2p23.3
Cellular Component: cilium; cytoplasm; Golgi apparatus; integral to membrane; integral to plasma membrane; membrane; plasma membrane
Molecular Function: adenylate cyclase activity
Biological Process: acrosome reaction; activation of protein kinase A; adenylate cyclase activation; cAMP biosynthetic process; cAMP-mediated signaling; G-protein signaling, adenylate cyclase activating pathway; G-protein signaling, adenylate cyclase inhibiting pathway; olfactory learning; renal water homeostasis; sensory perception of smell; signal transduction; single fertilization; sperm motility
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Product Notes
The ADCY3 adcy3 (Catalog #AAA555189) is an Antibody and is intended for research purposes only. The product is available for immediate purchase. The Adenylate Cyclase III/ADCY3, Antiserum, Rabbit reacts with Cat, Chicken, Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's Adenylate Cyclase III/ADCY3 can be used in a range of immunoassay formats including, but not limited to, Immunocytochemistry (ICC), Immunohistochemistry (IHC), Western Blot (WB). Researchers should empirically determine the suitability of the ADCY3 adcy3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Adenylate Cyclase III/ADCY3, Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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