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CRISPR system Cascade subunit CasA (casA) Recombinant Protein | casA recombinant protein

Recombinant Escherichia coli CRISPR system Cascade subunit CasA (casA)

Gene Names
casA; cse1; ECK2755; JW2730; ygcL
Purity
Greater or equal to 85% purity as determined by SDS-PAGE.
Synonyms
CRISPR system Cascade subunit CasA (casA); Recombinant Escherichia coli CRISPR system Cascade subunit CasA (casA); casA recombinant protein
Ordering
For Research Use Only!
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE.
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Sequence Positions
1-502, full length protein
Sequence
MNLLIDNWIPVRPRNGGKVQIINLQSLYCSRDQWRLSLPRDDMELAALALLVCIGQIIAPAKDDVEFRHRIMNPLTEDEFQQLIAPWIDMFYLNHAEHPFMQTKGVKANDVTPMEKLLAGVSGATNCAFVNQPGQGEALCGGCTAIALFNQANQAPGFGGGFKSGLRGGTPVTTFVRGIDLRSTVLLNVLTLPRLQKQFPNESHTENQPTWIKPIKSNESIPASSIGFVRGLFWQPAHIELCDPIGIGKCSCCGQESNLRYTGFLKEKFTFTVNGLWPHPHSPCLVTVKKGEVEEKFLAFTTSAPSWTQISRVVVDKIIQNENGNRVAAVVNQFRNIAPQSPLELIMGGYRNNQASILERRHDVLMFNQGWQQYGNVINEIVTVGLGYKTALRKALYTFAEGFKNKDFKGAGVSVHETAERHFYRQSELLIPDVLANVNFSQADEVIADLRDKLHQLCEMLFNQSVAPYAHHPKLISTLALARATLYKHLRELKPQGGPSNG
Sequence Length
502
Species
Escherichia coli (strain K12)
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
55,901 Da
NCBI Official Full Name
CRISP RNA (crRNA) containing Cascade antiviral complex protein
NCBI Official Symbol
casA
NCBI Official Synonym Symbols
cse1; ECK2755; JW2730; ygcL
NCBI Protein Information
CRISP RNA (crRNA) containing Cascade antiviral complex protein
UniProt Protein Name
CRISPR system Cascade subunit CasA
Protein Family
UniProt Gene Name
casA
UniProt Synonym Gene Names
cse1; ygcL

NCBI Description

The Cascade antiviral complex is comprised of CasABCDE and short CRISP RNAs (crRNAs) and requires the predicted helicase YgcB(Cas3) for activity (Brouns , 2008). [More information is available at EcoGene: EG13119]. Transcription is regulated by BaeR, which plays a role in novobiocin and deoxycholate resistance . [More information is available at EcoCyc: G7430].

Uniprot Description

CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).

Research Articles on casA

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Product Notes

The casA casa (Catalog #AAA1395932) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 1-502, full length protein. The amino acid sequence is listed below: MNLLIDNWIP VRPRNGGKVQ IINLQSLYCS RDQWRLSLPR DDMELAALAL LVCIGQIIAP AKDDVEFRHR IMNPLTEDEF QQLIAPWIDM FYLNHAEHPF MQTKGVKAND VTPMEKLLAG VSGATNCAFV NQPGQGEALC GGCTAIALFN QANQAPGFGG GFKSGLRGGT PVTTFVRGID LRSTVLLNVL TLPRLQKQFP NESHTENQPT WIKPIKSNES IPASSIGFVR GLFWQPAHIE LCDPIGIGKC SCCGQESNLR YTGFLKEKFT FTVNGLWPHP HSPCLVTVKK GEVEEKFLAF TTSAPSWTQI SRVVVDKIIQ NENGNRVAAV VNQFRNIAPQ SPLELIMGGY RNNQASILER RHDVLMFNQG WQQYGNVINE IVTVGLGYKT ALRKALYTFA EGFKNKDFKG AGVSVHETAE RHFYRQSELL IPDVLANVNF SQADEVIADL RDKLHQLCEM LFNQSVAPYA HHPKLISTLA LARATLYKHL RELKPQGGPS NG. It is sometimes possible for the material contained within the vial of "CRISPR system Cascade subunit CasA (casA), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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