Canine Vesicle-associated membrane protein 7 (VAMP7) ELISA Kit | VAMP7 elisa kit

Canine Vesicle-associated membrane protein 7 (VAMP7) ELISA Kit

Cat. Num. AAA7252146

• Gene Names: VAMP7; SYBL1; TIVAMP; VAMP-7; TI-VAMP
• Reactivity: Canine
• Synonyms: Vesicle-associated membrane protein 7 (VAMP7); Canine Vesicle-associated membrane protein 7 (VAMP7) ELISA Kit; VAMP7 elisa kit

• Reactivity: Canine

• Samples: Serum, plasma, Cell Culture Supernatants, body fluid and tissue homogenate
• Preparation and Storage: Store all reagents at 2-8 degree C.

Product Categories/Family for VAMP7 elisa kit

Signal Transduction

NCBI and Uniprot Product Information

• NCBI GI #: 1723133
• NCBI GeneID: 6845
• Molecular Weight: 20,121 Da
• NCBI Official Full Name: Vesicle-associated membrane protein 7
• NCBI Official Synonym Full Names: vesicle-associated membrane protein 7
• NCBI Official Symbol: VAMP7
• NCBI Official Synonym Symbols: SYBL1; TIVAMP; VAMP-7; TI-VAMP
• NCBI Protein Information: vesicle-associated membrane protein 7; synaptobrevin-like 1; tetanus-insensitive VAMP; synaptobrevin-like protein 1; tetanus neurotoxin-insensitive VAMP
• UniProt Protein Name: Vesicle-associated membrane protein 7
• Protein Family: Vesicle-associated membrane protein
• UniProt Gene Name: VAMP7
• UniProt Synonym Gene Names: SYBL1; VAMP-7; Ti-VAMP
• UniProt Entry Name: VAMP7_HUMAN

NCBI Description

This gene encodes a transmembrane protein that is a member of the soluble N-ethylmaleimide-sensitive factor attachment protein receptor (SNARE) family. The encoded protein localizes to late endosomes and lysosomes and is involved in the fusion of transport vesicles to their target membranes. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Jun 2010]

Uniprot Description

VAMP7: Involved in the targeting and/or fusion of transport vesicles to their target membrane during transport of proteins from the early endosome to the lysosome. Required for heterotypic fusion of late endosomes with lysosomes and homotypic lysosomal fusion. Required for calcium regulated lysosomal exocytosis. Involved in the export of chylomicrons from the endoplasmic reticulum to the cis Golgi. Required for exocytosis of mediators during eosinophil and neutrophil degranulation, and target cell killing by natural killer cells. Required for focal exocytosis of late endocytic vesicles during phagosome formation. Belongs to the synaptobrevin family. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral

Chromosomal Location of Human Ortholog: Xq28 and Yq12

Cellular Component: Golgi apparatus; endoplasmic reticulum membrane; neuron projection; cell surface; intracellular membrane-bound organelle; late endosome membrane; secretory granule membrane; lysosomal membrane; integral to membrane; phagocytic vesicle; pseudopodium; trans-Golgi network; secretory granule; SNARE complex; phagocytic vesicle membrane; membrane; apical part of cell; perinuclear region of cytoplasm; lamellipodium; cytoplasm; plasma membrane; synapse; cell junction

Molecular Function: SNAP receptor activity; SNARE binding; protein binding; syntaxin binding

Biological Process: ER to Golgi vesicle-mediated transport; exocytosis; autophagic vacuole fusion; natural killer cell degranulation; neutrophil degranulation; endocytosis; vesicle fusion with Golgi apparatus; calcium ion-dependent exocytosis; vesicle fusion; vesicle-mediated transport; Golgi to plasma membrane protein transport; eosinophil degranulation; endosome to lysosome transport; triacylglycerol transport; post-Golgi vesicle-mediated transport; phagocytosis, engulfment