Canine Neuronal Acetylcholine Receptor Subunit Alpha-6 (CHRNA6) ELISA Kit | CHRNA6 elisa kit
Canine Neuronal Acetylcholine Receptor Subunit Alpha-6 (CHRNA6) ELISA Kit
NCBI and Uniprot Product Information
NCBI Description
This gene encodes an alpha subunit of neuronal nicotinic acetylcholine receptors. These receptors consist of five subunits and function as ion channels involved in neurotransmission. The encoded protein is a subunit of neuronal nicotinic acetylcholine receptors that mediate dopaminergic neurotransmission and are activated by acetylcholine and exogenous nicotine. Alternatively spliced transcript variants have been observed for this gene. Single nucleotide polymorphisms in this gene have been associated with both nicotine and alcohol dependence. [provided by RefSeq, Dec 2010]
Uniprot Description
nAChRA6: After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. Belongs to the ligand-gated ion channel (TC 1.A.9) family. Acetylcholine receptor (TC 1.A.9.1) subfamily. Alpha- 6/CHRNA6 sub-subfamily. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Channel, ligand-gated; Membrane protein, integral; Membrane protein, multi-pass
Chromosomal Location of Human Ortholog: 8p11.21
Cellular Component: plasma membrane
Molecular Function: acetylcholine binding; acetylcholine receptor activity; ligand-gated ion channel activity
Biological Process: neuromuscular synaptic transmission; response to nicotine; signal transduction; synaptic transmission; synaptic transmission, cholinergic; transport
Research Articles on CHRNA6
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Product Notes
The Canine CHRNA6 chrna6 (Catalog #AAA9391800) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9391800 ELISA Kit recognizes Canine CHRNA6. It is sometimes possible for the material contained within the vial of "Neuronal Acetylcholine Receptor Subunit Alpha-6 (CHRNA6), ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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