Canine Lipid phosphate phosphohydrolase 1 (PPAP2A) ELISA Kit | PPAP2A elisa kit
Canine Lipid phosphate phosphohydrolase 1 (PPAP2A) ELISA Kit
NCBI and Uniprot Product Information
Uniprot Description
PPAP2A: Broad-specificity phosphohydrolase that dephosphorylates exogenous bioactive glycerolipids and sphingolipids. Catalyzes the conversion of phosphatidic acid (PA) to diacylglycerol (DG). Pivotal regulator of lysophosphatidic acid (LPA) signaling in the cardiovascular system. Major enzyme responsible of dephosphorylating LPA in platelets, which terminates signaling actions of LPA. May control circulating, and possibly also regulate localized, LPA levels resulting from platelet activation. It has little activity towards ceramide-1-phosphate (C-1-P) and sphingosine-1-phosphate (S-1-P). The relative catalytic efficiency is LPA > PA > S-1-P > C-1-P. It's down-regulation may contribute to the development of colon adenocarcinoma. Belongs to the PA-phosphatase related phosphoesterase family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Lipid Metabolism - sphingolipid; Membrane protein, multi-pass; EC 3.1.3.4; Phosphatase (non-protein); Lipid Metabolism - ether lipid; Motility/polarity/chemotaxis; Membrane protein, integral; Lipid Metabolism - glycerophospholipid; Lipid Metabolism - glycerolipid
Cellular Component: membrane; integral to plasma membrane; integral to membrane; plasma membrane
Molecular Function: hydrolase activity; phosphatidate phosphatase activity; catalytic activity
Biological Process: dephosphorylation; diacylglycerol biosynthetic process; sphingosine metabolic process; lipid metabolic process; signal transduction; ceramide metabolic process; protein amino acid dephosphorylation
Research Articles on PPAP2A
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Product Notes
The Canine PPAP2A ppap2a (Catalog #AAA7233070) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA7233070 ELISA Kit recognizes Canine PPAP2A. It is sometimes possible for the material contained within the vial of "Lipid phosphate phosphohydrolase 1 (PPAP2A), ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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