Canine COUP transcription factor 2 (NR2F2) ELISA Kit | NR2F2 elisa kit
Canine COUP transcription factor 2 (NR2F2) ELISA Kit
NCBI and Uniprot Product Information
Uniprot Description
NR2F2: Ligand-activated transcription factor. Activated by high concentrations of 9-cis-retinoic acid and all-trans-retinoic acid, but not by dexamethasone, cortisol or progesterone (in vitro). Regulation of the apolipoprotein A-I gene transcription. Binds to DNA site A. Interacts with SQSTM1. Binds DNA as a dimer; homodimer or heterodimer with NR2F6. Interacts with NCOA1, NCOA2, NCOA3 and PPARGC1A. Interacts with ZFPM2. Ubiquitous. Belongs to the nuclear hormone receptor family. NR2 subfamily. 3 isoforms of the human protein are produced by alternative splicing.
Protein type: Nuclear receptor; Motility/polarity/chemotaxis; DNA-binding
Cellular Component: nucleus
Molecular Function: ligand-dependent nuclear receptor activity; retinoic acid binding; protein homodimerization activity; DNA binding; zinc ion binding; sequence-specific DNA binding; metal ion binding; steroid hormone receptor activity; transcription factor activity
Biological Process: transcription from RNA polymerase II promoter; limb development; skeletal muscle development; intracellular receptor-mediated signaling pathway; transcription, DNA-dependent; in utero embryonic development; positive regulation of transcription, DNA-dependent; negative regulation of cyclin-dependent protein kinase activity; neuron migration; negative regulation of transcription from RNA polymerase II promoter; anterior/posterior pattern formation; regulation of transcription from RNA polymerase II promoter; fertilization; regulation of transcription, DNA-dependent; forebrain development; negative regulation of endothelial cell proliferation; blood vessel morphogenesis; steroid hormone mediated signaling; negative regulation of transcription, DNA-dependent; radial pattern formation; maternal placenta development