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Canine Corticosteroid Binding Globulin (CBG) ELISA Kit | SERPINA6 elisa kit

Canine Corticosteroid Binding Globulin (CBG) ELISA Kit

Gene Names
SERPINA6; CBG
Reactivity
Canine
Synonyms
Corticosteroid Binding Globulin (CBG); Canine Corticosteroid Binding Globulin (CBG) ELISA Kit; SERPINA6 elisa kit
Ordering
For Research Use Only!
Reactivity
Canine
Samples
Serum, plasma, Cell Culture Supernatants, body fluid and tissue homogenate
Assay Type
Competitive
Detection Range
5.0-100ng/mL
Sensitivity
1.0ng/mL
Preparation and Storage
Store all reagents at 2-8 degree C.
Product Categories/Family for SERPINA6 elisa kit

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
866
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
45,141 Da
NCBI Official Full Name
corticosteroid-binding globulin
NCBI Official Synonym Full Names
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 6
NCBI Official Symbol
SERPINA6
NCBI Official Synonym Symbols
CBG
NCBI Protein Information
corticosteroid-binding globulin; serpin A6; transcortin; corticosteroid binding globulin; serine (or cysteine) proteinase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 6
UniProt Protein Name
Corticosteroid-binding globulin
UniProt Gene Name
SERPINA6
UniProt Synonym Gene Names
CBG; CBG
UniProt Entry Name
CBG_HUMAN

NCBI Description

This gene encodes an alpha-globulin protein with corticosteroid-binding properties. This is the major transport protein for glucorticoids and progestins in the blood of most vertebrates. The gene localizes to a chromosomal region containing several closely related serine protease inhibitors which may have evolved by duplication events. [provided by RefSeq, Jul 2008]

Uniprot Description

SERPINA6: Major transport protein for glucocorticoids and progestins in the blood of almost all vertebrate species. Defects in SERPINA6 are a cause of corticosteroid-binding globulin deficiency (CBG deficiency). CBG deficiency is an extremely rare hereditary disorder characterized by reduced corticosteroid-binding capacity with normal or low plasma corticosteroid-binding globulin concentration, and normal or low basal cortisol levels associated with hypo/hypertension and muscle fatigue. Belongs to the serpin family.

Protein type: Secreted; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 14q32.1

Cellular Component: extracellular space

Molecular Function: serine-type endopeptidase inhibitor activity; steroid binding

Biological Process: glucocorticoid metabolic process; transport

Disease: Corticosteroid-binding Globulin Deficiency

Research Articles on SERPINA6

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Product Notes

The Canine SERPINA6 serpina6 (Catalog #AAA7213466) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA7213466 ELISA Kit recognizes Canine SERPINA6. It is sometimes possible for the material contained within the vial of "Corticosteroid Binding Globulin (CBG), ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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