Camel Probable Ubiquitin Carboxyl-Terminal Hydrolase FAF-X (USP9X) ELISA Kit | USP9X elisa kit
Camel Probable Ubiquitin Carboxyl-Terminal Hydrolase FAF-X (USP9X) ELISA Kit
NCBI and Uniprot Product Information
NCBI Description
This gene is a member of the peptidase C19 family and encodes a protein that is similar to ubiquitin-specific proteases. Though this gene is located on the X chromosome, it escapes X-inactivation. Mutations in this gene have been associated with Turner syndrome. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]
Uniprot Description
USP9X: Deubiquitinase involved both in the processing of ubiquitin precursors and of ubiquitinated proteins. May therefore play an important role regulatory role at the level of protein turnover by preventing degradation of proteins through the removal of conjugated ubiquitin. Essential component of TGF-beta/BMP signaling cascade. Regulates chromosome alignment and segregation in mitosis by regulating the localization of BIRC5/survivin to mitotic centromeres. Specifically hydrolyzes both 'Lys-29'- and 'Lys-33'-linked polyubiquitins chains. Specifically deubiquitinates monoubiquitinated SMAD4, opposing the activity of E3 ubiquitin-protein ligase TRIM33. Interacts with SMAD4, MARK4, NUAK1 and BIRC5/survivin. Widely expressed in embryonic and adult tissues. Belongs to the peptidase C19 family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Protease; Ubiquitin conjugating system; EC 3.4.19.12; Ubiquitin-specific protease
Chromosomal Location of Human Ortholog: Xp11.4
Cellular Component: apical part of cell; cytoplasm; cytosol; growth cone; membrane
Molecular Function: cysteine-type endopeptidase activity; cysteine-type peptidase activity; protein binding; ubiquitin-specific protease activity
Biological Process: axon extension; BMP signaling pathway; cell division; cellular protein metabolic process; cerebellar cortex structural organization; chromosome segregation; female gamete generation; gene expression; hippocampus development; in utero embryonic development; mitosis; negative regulation of transcription from RNA polymerase II promoter; neuron migration; post-embryonic development; protein deubiquitination; transcription initiation from RNA polymerase II promoter; transcription, DNA-dependent; transforming growth factor beta receptor signaling pathway; ubiquitin-dependent protein catabolic process
Disease: Mental Retardation, X-linked 99
Research Articles on USP9X
Similar Products
Product Notes
The Camel USP9X usp9x (Catalog #AAA9346812) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9346812 ELISA Kit recognizes Camel USP9X. It is sometimes possible for the material contained within the vial of "Probable Ubiquitin Carboxyl-Terminal Hydrolase FAF-X (USP9X), ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.
