Camel Nuclear Prelamin A Recognition Factor (NARF) ELISA Kit | NARF elisa kit
Camel Nuclear Prelamin A Recognition Factor (NARF) ELISA Kit
NCBI and Uniprot Product Information
Uniprot Description
NARF: Several proteins have been found to be prenylated and methylated at their carboxyl-terminal ends. Prenylation was initially believed to be important only for membrane attachment. However, another role for prenylation appears to be its importance in protein-protein interactions. The only nuclear proteins known to be prenylated in mammalian cells are prelamin A- and B-type lamins. Prelamin A is farnesylated and carboxymethylated on the cysteine residue of a carboxyl-terminal CaaX motif. This post-translationally modified cysteine residue is removed from prelamin A when it is endoproteolytically processed into mature lamin A. The protein encoded by this gene binds to the prenylated prelamin A carboxyl-terminal tail domain. It may be a component of a prelamin A endoprotease complex. The encoded protein is located in the nucleus, where it partially colocalizes with the nuclear lamina. It shares limited sequence similarity with iron-only bacterial hydrogenases. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene, including one with a novel exon that is generated by RNA editing. [provided by RefSeq, Jul 2008]
Chromosomal Location of Human Ortholog: 17q25.3
Cellular Component: cytosol; lamin filament; nuclear lamina; nuclear lumen
Molecular Function: iron-sulfur cluster binding; lamin binding; NADH dehydrogenase activity
Biological Process: iron-sulfur cluster assembly
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Product Notes
The Camel NARF narf (Catalog #AAA9347574) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9347574 ELISA Kit recognizes Camel NARF. It is sometimes possible for the material contained within the vial of "Nuclear Prelamin A Recognition Factor (NARF), ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
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