Calcitonin Recombinant Protein | LRP1 recombinant protein

Calcitonin, Human (Synthetic peptide)

Cat. Num. AAA8400056

• Gene Names: CALCA; CT; KC; CGRP; CALC1; CGRP1; CGRP-I
• Purity: >95% by HPLC
• Synonyms: Calcitonin; Human (Synthetic peptide); LRP1 recombinant protein

• Host: Synthetic peptide
• Purity/Purification: >95% by HPLC
• Form/Format: Lyophilized powder. Lyophilized in 0.05% TFA in Acetonitrile/water
• Sequence Positions: aa85-116

• Gene Source: Human
• Preparation and Storage: The lyophilized human Calcitonin is very stable at -20 degree C. Upon reconstitution the material should be aliquoted and freeze at -80 degree C. It is recommended to add a carrier protein (0.1% HSA or BSA) for long term storage.; Centrifuge the vial prior to opening.; Shelf life: ~12 months

Testing Data

Testing Data

Related Product Information for LRP1 recombinant protein

IDL functions in the endogenous lipid transport system. It is the particle resulting from the interaction of VLDL and lipoprotein lipase. When IDL receives cholesteryl esters from HDL, it is converted to cholesteryl ester-rich LDL. Peptide hormone that inhibits the activity of osteoclasts, first messenger to regulate adenylyl cyclase/cAMP

Product Categories/Family for LRP1 recombinant protein

Proteins; Enzymes; Lipoproteins; Proteins & Enzymes (A-Z); Native Proteins

NCBI and Uniprot Product Information

• NCBI GI #: 76880484
• NCBI GeneID: 796
• NCBI Accession #: NP_001029124.1
• NCBI GenBank Nucleotide #: NM_001033952.2
• UniProt Accession #: P01258; Q13935; Q13937; Q52LX7; B7ZL39; P06881
• Molecular Weight: 15,466 Da
• NCBI Official Full Name: calcitonin isoform CT preproprotein
• NCBI Official Synonym Full Names: calcitonin-related polypeptide alpha
• NCBI Official Symbol: CALCA
• NCBI Official Synonym Symbols: CT; KC; CGRP; CALC1; CGRP1; CGRP-I
• NCBI Protein Information: calcitonin; calcitonin gene-related peptide 1; katacalcin; calcitonin 1; alpha-type CGRP; calcitonin gene-related peptide I; calcitonin/calcitonin-related polypeptide, alpha
• UniProt Protein Name: Calcitonin
• Protein Family: Calcitonin
• UniProt Gene Name: CALCA
• UniProt Synonym Gene Names: CALC1; CCP
• UniProt Entry Name: CALC_HUMAN

NCBI Description

This gene encodes the peptide hormones calcitonin, calcitonin gene-related peptide and katacalcin by tissue-specific alternative RNA splicing of the gene transcripts and cleavage of inactive precursor proteins. Calcitonin is involved in calcium regulation and acts to regulate phosphorus metabolism. Calcitonin gene-related peptide functions as a vasodilator while katacalcin is a calcium-lowering peptide. Multiple transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Nov 2009]

Uniprot Description

CALCA: Calcitonin causes a rapid but short-lived drop in the level of calcium and phosphate in blood by promoting the incorporation of those ions in the bones. Belongs to the calcitonin family. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Secreted, signal peptide; Secreted

Chromosomal Location of Human Ortholog: 11p15.2

Cellular Component: extracellular space; cell soma; cytoplasm; extracellular region; terminal button; nucleus

Molecular Function: identical protein binding; protein binding; calcitonin receptor binding; hormone activity; protein complex binding; receptor binding

Biological Process: negative regulation of osteoclast differentiation; elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating); positive regulation of interleukin-1 alpha production; vasodilation of artery during baroreceptor response to increased systemic arterial blood pressure; response to pain; positive regulation of vasodilation; protein amino acid phosphorylation; G-protein signaling, adenylate cyclase activating pathway; positive regulation of interleukin-8 production; monocyte chemotaxis; elevation of cytosolic calcium ion concentration; leukocyte adhesion; cell-cell signaling; vasculature development; neuropeptide signaling pathway; negative regulation of smooth muscle contraction; receptor internalization; regulation of blood pressure; positive regulation of cAMP biosynthetic process; negative regulation of ossification; feeding behavior; negative regulation of blood pressure; positive regulation of adenylate cyclase activity; positive regulation of macrophage differentiation; negative regulation of bone resorption; detection of temperature stimulus involved in sensory perception of pain; inflammatory response; negative regulation of neurological process; aging; cytosolic calcium ion homeostasis; regulation of heart rate; adenylate cyclase activation; positive regulation of ossification; regulation of systemic arterial blood pressure by neurological process; G-protein coupled receptor internalization; response to heat; endothelial cell proliferation; regulation of inflammatory response; activation of protein kinase activity; endothelial cell migration; negative regulation of transcription, DNA-dependent; embryo implantation