Hepatitis B Virus Core Delta Recombinant Protein | HBcAg recombinant protein
Recombinant Hepatitis B Virus Core Delta
Applications
ELISA, Western Blot
Purity
HBV Core Delta protein is >95% pure as determined by 10% PAGE (coomassie staining).Purified by proprietary chromatographic technique.
Synonyms
Hepatitis B Virus Core Delta; Recombinant Hepatitis B Virus Core Delta; HBV core delta; Hepatitis B Virus Core delta Recombinant; HBcAg Delta; HBcAg recombinant protein
Specificity
Immunoreactive with sera HBV-infected individuals.
Purity/Purification
HBV Core Delta protein is >95% pure as determined by 10% PAGE (coomassie staining).
Purified by proprietary chromatographic technique.
Purified by proprietary chromatographic technique.
Form/Format
7.5mM Phosphate buffer pH-7.2, 75mM NaCl, & 50% glycerol.
Sequence Length
40
Applicable Applications for HBcAg recombinant protein
ELISA (EIA), Western Blot (WB)
Application Notes
HBV Core Delta antigen is suitable for ELISA and Western blots, excellent antigen for detection of HBV with minimal specificity problems.
Related Product Information for HBcAg recombinant protein
Description: The E Coli derived 14kDa recombinant protein contains the HBV core delta ayw immunodominant region amino acids 1-144.
Introduction: Hepatitis B is one of a few known non-retroviralviruses which employ reverse transcriptionas a part of its replication process. (HIV, a completely unrelated virus, also uses reverse transcription, but it is a retrovirus.) HBV invades the cell by binding to surface receptor and become internalized. The viral core particles then migrate to the hepatocyte nucleus and the partially double-stranded, relaxed circular genomes (RC-DNA) are repaired to form a covalently closed circular DNA (cccDNA), which is the template for viral genomic and sub-genomic RNAs by cellular RNA polymerase II. Of these, the pregenomic RNA (pgRNA is selectively packaged into progeny capsids and is then reverse-transcribed into new RC-DNA. The core can either bud into the endoplasmic reticulum to be enveloped or exported from the cell or recycled back into the genome for conversion to cccDNA.
Introduction: Hepatitis B is one of a few known non-retroviralviruses which employ reverse transcriptionas a part of its replication process. (HIV, a completely unrelated virus, also uses reverse transcription, but it is a retrovirus.) HBV invades the cell by binding to surface receptor and become internalized. The viral core particles then migrate to the hepatocyte nucleus and the partially double-stranded, relaxed circular genomes (RC-DNA) are repaired to form a covalently closed circular DNA (cccDNA), which is the template for viral genomic and sub-genomic RNAs by cellular RNA polymerase II. Of these, the pregenomic RNA (pgRNA is selectively packaged into progeny capsids and is then reverse-transcribed into new RC-DNA. The core can either bud into the endoplasmic reticulum to be enveloped or exported from the cell or recycled back into the genome for conversion to cccDNA.
Product Categories/Family for HBcAg recombinant protein
NCBI and Uniprot Product Information
NCBI GI #
Molecular Weight
4,756 Da
NCBI Official Full Name
HBcAg, partial
UniProt Protein Name
HBcAg
UniProt Gene Name
C
UniProt Entry Name
L8E6H4_HBV
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Product Notes
The HBcAg c (Catalog #AAA142514) is a Recombinant Protein and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's Hepatitis B Virus Core Delta can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB). HBV Core Delta antigen is suitable for ELISA and Western blots, excellent antigen for detection of HBV with minimal specificity problems. Researchers should empirically determine the suitability of the HBcAg c for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Hepatitis B Virus Core Delta, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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