Phospholipase A2 Recombinant Protein | PA2-BVP recombinant protein
Recombinant Phospholipase A2 P00630 Bee Venom Protein
Gene Names
Pla2; bvPLA2; GB13351
Purity
Protein is >90% pure as determined by 10% SDS-PAGE.Purified by proprietary chromatographic technique.
Synonyms
Phospholipase A2; Recombinant Phospholipase A2 P00630 Bee Venom Protein; Phospholipase A2 P00630 Bee Venom Protein Recombinant; Phosphatidylcholine 2-acylhydrolase; Allergen Api m I; Api m 1; PA2-BVP recombinant protein
Host
E Coli
Purity/Purification
Protein is >90% pure as determined by 10% SDS-PAGE.
Purified by proprietary chromatographic technique.
Purified by proprietary chromatographic technique.
Form/Format
20mM Tris-HCl, pH 7.2, 1.5M urea and 50% glycerol.
Sequence Length
167
Preparation and Storage
Phospholipase A2 although stable at 4 degree C for 1 week, should be stored below -18 degree C. Please prevent freeze thaw cycles.
Related Product Information for PA2-BVP recombinant protein
Description: The E Coli derived recombinant protein contains phospholipase P00630 bee venom protein epitopes, 26-162 amino acids.
Introduction: Bee venom phospholipase A2 (PLA) is the main allergen in the bee sting allergy. Bee venom phospholipase A2 (BV-PLA2) is a hydrolytic enzyme which specifically cleaves the sn-2 acyl bond of phospholipids at the lipid/water interface. BV-PLA2 is a 1416-kDa glycoprotein, consisting of 134 amino acids and displaying a single carbohydrate side chain at the residue Asn13. It is also held to be responsible for some systemic anaphylactic reactions in bee venom sensitized individuals. BV-PLA2 presents 3 peptide and a glycopeptide T cell epitopes, which are recognized by both allergic and non-allergic bee venom sensitized subjects. PLA is able to elicit both IgE mediated allergy and normal immunity to bee sting which usually is associated with high affinity IgG4 anti-PLA antibodies.
Introduction: Bee venom phospholipase A2 (PLA) is the main allergen in the bee sting allergy. Bee venom phospholipase A2 (BV-PLA2) is a hydrolytic enzyme which specifically cleaves the sn-2 acyl bond of phospholipids at the lipid/water interface. BV-PLA2 is a 1416-kDa glycoprotein, consisting of 134 amino acids and displaying a single carbohydrate side chain at the residue Asn13. It is also held to be responsible for some systemic anaphylactic reactions in bee venom sensitized individuals. BV-PLA2 presents 3 peptide and a glycopeptide T cell epitopes, which are recognized by both allergic and non-allergic bee venom sensitized subjects. PLA is able to elicit both IgE mediated allergy and normal immunity to bee sting which usually is associated with high affinity IgG4 anti-PLA antibodies.
Product Categories/Family for PA2-BVP recombinant protein
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
19,058 Da
NCBI Official Full Name
phospholipase A2
NCBI Official Synonym Full Names
phospholipase A2<
NCBI Official Symbol
Pla2
NCBI Official Synonym Symbols
bvPLA2; GB13351
NCBI Protein Information
phospholipase A2; allergen Api m 1; allergen Api m I; phosphatidylcholine 2-acylhydrolase
UniProt Protein Name
Phospholipase A2
Protein Family
UniProt Gene Name
bvPLA2
UniProt Synonym Gene Names
bvPLA2
UniProt Entry Name
PA2_APIME
Uniprot Description
PLA2 catalyzes the calcium-dependent hydrolysis of the 2-acyl groups in 3-sn-phosphoglycerides.
Research Articles on PA2-BVP
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Product Notes
The PA2-BVP bvpla2 (Catalog #AAA142001) is a Recombinant Protein produced from E Coli and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "Phospholipase A2, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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