Blood vessel epicardial substance (BVES) Recombinant Protein | BVES recombinant protein
Recombinant Pig Blood vessel epicardial substance (BVES)
NCBI and Uniprot Product Information
Uniprot Description
Function: Cell adhesion molecule involved in the establishment and/or maintenance of cell integrity. Involved in the formation and regulation of the tight junction (TJ) paracellular permeability barrier in epithelial cells. Plays a role in VAMP3-mediated vesicular transport and recycling of different receptor molecules through its interaction with VAMP3. Plays a role in the regulation of cell shape and movement by modulating the Rho-family GTPase activity through its interaction with ARHGEF25/GEFT. Induces primordial adhesive contact and aggregation of epithelial cells in a Ca2+-independent manner. Also involved in striated muscle regeneration and repair and in the regulation of cell spreading
By similarity.
Subunit structure: Homodimer. Homodimerization requires the C-terminus cytoplasmic region. Interacts (via the C-terminus cytoplasmic tail) with TJP1. Interacts (via the C-terminus cytoplasmic tail) with ARHGEF25/GEFT (via the DH domain). Interacts (via the C-terminus cytoplasmic tail) with VAMP3
By similarity.
Subcellular location: Lateral cell membrane
By similarity. Cell junction › tight junction
By similarity. Membrane; Multi-pass membrane protein
Potential. Note: Its movement from the cytoplasm to membrane is an early event occurring concurrently with cell-cell contact. Detected at cell-cell contact but never observed at the free surface of epithelial cells. Colocalizes in epithelial cells with OCLN and TJP1 in an apical-lateral position within the z axis. Colocalizes with VAMP3 at the cell-cell contact in cardiac and skeletal muscle
By similarity.
Sequence similarities: Belongs to the popeye family.
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Product Notes
The BVES bves (Catalog #AAA1180811) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 1-360. The amino acid sequence is listed below: MNYTESSPLA ESTAIGFTPE LGSITPVPSN ETTCENWREI HHLVFHVANV FFAIGLVLPT TLHLHMILLR GMLTIGCTLY IVWATLYRCA LDIMIWNSVF LGINVLHLSY LLYKKRPVKI EKELKGIYQR LFEPLRVPPD LFKRLTGQFC MIQTLKKGQA YAAEDKTSVD DRLSILLKGK MKVSYRGHFL HNIYPCAFID SPEFRSTQMH KGEKFQVTII ADDNCRFLCW SRERLTYFLE SEPFLYEVFR YLIGKDITNK LYSLNDPTLN DKTIKKLDHQ LSLCTQLSML EMRNSIVSTS DSEDGLHQFL RGTSSVSSLY VPSPHQRASA KMKPIEEGVE DDDEVFEPET PNTFKVRQLP. It is sometimes possible for the material contained within the vial of "Blood vessel epicardial substance (BVES), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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