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Mouse Blood vessel epicardial substance ELISA Kit | BVES elisa kit

Mouse Blood vessel epicardial substance (BVES) ELISA Kit

Gene Names
Bves; Pop1; mBVES; Popdc1
Reactivity
Mouse
Synonyms
Blood vessel epicardial substance; Mouse Blood vessel epicardial substance (BVES) ELISA Kit; HBVES; MGC42413; POP1; POPDC1; popeye domain containing 1|popeye protein 1; BVES elisa kit
Ordering
For Research Use Only!
Reactivity
Mouse
Specificity
This assay has high sensitivity and excellent specificity for detection of Mouse BVES. No significant cross-reactivity or interference between Mouse BVES and analogues was observed.
Sequence Length
360
Samples
Serum, Plasma, Other biological fluids
Assay Type
Sandwich
Sample Volume
1-200 uL
Precision
Intra-assay Precision (Precision within an assay)
Three samples of known concentration were tested twenty times on one plate to assess intra-assay precision.
Inter-assay Precision (Precision between assays)
Three samples of known concentration were tested in forty separate assays to assess inter-assay precision.
CV (%) = SD/meanX100
Intra-Assay: CV
Inter-Assay: CV
Detection Wavelength
450 nm
Preparation and Storage
Store at 2-8 degree C.
Related Product Information for BVES elisa kit
Principle of the Assay: This assay employs a two-site sandwich ELISA to quantitate BVES in samples. An antibody specific for BVES has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and anyBVES present is bound by the immobilized antibody. After removing any unbound substances, a biotin-conjugated antibody specific for BVES is added to the wells. After washing, Streptavidin conjugated Horseradish Peroxidase (HRP) is added to the wells. Following a wash to remove any unbound avidin-enzyme reagent, a substrate solution is added to the wells and color develops in proportion to the amount of BVES bound in the initial step. The color development is stopped and the intensity of the color is measured.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
41,016 Da
NCBI Official Full Name
blood vessel epicardial substance
NCBI Official Synonym Full Names
blood vessel epicardial substance
NCBI Official Symbol
Bves
NCBI Official Synonym Symbols
Pop1; mBVES; Popdc1
NCBI Protein Information
blood vessel epicardial substance
UniProt Protein Name
Blood vessel epicardial substance
UniProt Gene Name
Bves
UniProt Synonym Gene Names
mBVES; Popeye protein 1

Uniprot Description

BVES: Cell adhesion molecule involved in the establishment and/or maintenance of cell integrity. Involved in the formation and regulation of the tight junction (TJ) paracellular permeability barrier in epithelial cells. Plays a role in VAMP3- mediated vesicular transport and recycling of different receptor molecules through its interaction with VAMP3. Plays a role in the regulation of cell shape and movement by modulating the Rho-family GTPase activity through its interaction with ARHGEF25/GEFT. Induces primordial adhesive contact and aggregation of epithelial cells in a Ca(2+)-independent manner. Also involved in striated muscle regeneration and repair and in the regulation of cell spreading. Belongs to the popeye family.

Protein type: Membrane protein, integral; Membrane protein, multi-pass

Chromosomal Location of Human Ortholog: 10 B2|10 23.47 cM

Cellular Component: bicellular tight junction; caveola; cell junction; cell projection membrane; integral component of membrane; lateral plasma membrane; membrane; plasma membrane; sarcolemma

Molecular Function: cAMP binding; nucleotide binding; protein binding; structural molecule activity

Biological Process: cell adhesion; heart development; hemopoietic progenitor cell differentiation; multicellular organism development; positive regulation of locomotion; positive regulation of receptor recycling; regulation of cell shape; regulation of GTPase activity; regulation of heart rate; regulation of membrane potential; skeletal muscle tissue development; vesicle docking; vesicle-mediated transport

Research Articles on BVES

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Product Notes

The Mouse BVES bves (Catalog #AAA284259) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA284259 ELISA Kit recognizes Mouse BVES. It is sometimes possible for the material contained within the vial of "Blood vessel epicardial substance, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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