Human B-cell translocation gene 1, proliferative ELISA Kit | BTG1 elisa kit

Human Protein BTG1, BTG1 ELISA Kit

Cat. Num. AAA9337033

• Reactivity: Human
• Synonyms: B-cell translocation gene 1; proliferative; Human Protein BTG1; BTG1 ELISA Kit; Human Protein BTG1 (BTG1) ELISA kit; B-cell translocation protein 1; BTG1 elisa kit

• Reactivity: Human
• Specificity: No significant cross-reactivity or interference between this analyte and analogues is observed.

• Samples: Body fluids, tissue homogenates, secretions or feces samples
• Assay Type: Quantitative Sandwich
• Detection Range: 3.12 ng/ml - 100 ng/ml
• Sensitivity: 1.0 ng/ml.
• Intra-assay Precision: Intra-assay CV (%) is less than 15%
• Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100].
• Preparation and Storage: Store all reagents at 2-8 degree C

Related Product Information for BTG1 elisa kit

Background/Introduction: This Quantitative Sandwich ELISA kit is only for in vitro research use only! This kit is intended to be used for determination the level of BTG1 (hereafter termed "analyte") in undiluted original Human body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances.

NCBI and Uniprot Product Information

• NCBI GI #: 4502473
• NCBI GeneID: 694
• NCBI Accession #: NP_001722.1
• NCBI GenBank Nucleotide #: NM_001731.2
• UniProt Accession #: P62324; P31607
• Molecular Weight: 19,209 Da
• NCBI Official Full Name: protein BTG1
• NCBI Official Synonym Full Names: B-cell translocation gene 1, anti-proliferative
• NCBI Official Symbol: BTG1
• NCBI Protein Information: protein BTG1; B-cell translocation gene 1 protein
• UniProt Protein Name: Protein BTG1
• Protein Family: Protein
• UniProt Gene Name: BTG1
• UniProt Entry Name: BTG1_HUMAN

NCBI Description

This gene is a member of an anti-proliferative gene family that regulates cell growth and differentiation. Expression of this gene is highest in the G0/G1 phases of the cell cycle and downregulated when cells progressed through G1. The encoded protein interacts with several nuclear receptors, and functions as a coactivator of cell differentiation. This locus has been shown to be involved in a t(8;12)(q24;q22) chromosomal translocation in a case of B-cell chronic lymphocytic leukemia. [provided by RefSeq, Oct 2008]

Uniprot Description

BTG1: Anti-proliferative protein. A chromosomal aberration involving BTG1 may be a cause of a form of B-cell chronic lymphocytic leukemia. Translocation t(8;12)(q24;q22) with MYC. Belongs to the BTG family.

Protein type: Oncoprotein; Cell cycle regulation

Chromosomal Location of Human Ortholog: 12q22

Cellular Component: cytoplasm; nucleus

Molecular Function: protein binding; enzyme binding; transcription cofactor activity; kinase binding

Biological Process: negative regulation of cell proliferation; cell migration; positive regulation of angiogenesis; positive regulation of endothelial cell differentiation; regulation of transcription, DNA-dependent; negative regulation of cell growth; positive regulation of myoblast differentiation