Bovine Melanocortin Receptor 3 (MC3R) ELISA Kit | MC3R elisa kit

Bovine Melanocortin Receptor 3 (MC3R) ELISA Kit

Cat. Num. AAA9361058

• Gene Names: MC3R; MC3; OB20; OQTL; BMIQ9; MC3-R
• Reactivity: Bovine
• Synonyms: Melanocortin Receptor 3 (MC3R); Bovine Melanocortin Receptor 3 (MC3R) ELISA Kit; MC3R elisa kit

• Reactivity: Bovine

• Preparation and Storage: Store all reagents at 2-8 degree C

NCBI and Uniprot Product Information

• NCBI GI #: 170671732
• NCBI GeneID: 4159
• NCBI Accession #: NP_063941.3
• NCBI GenBank Nucleotide #: NM_019888.3
• Molecular Weight: 36,043 Da
• NCBI Official Full Name: melanocortin receptor 3
• NCBI Official Synonym Full Names: melanocortin 3 receptor
• NCBI Official Symbol: MC3R
• NCBI Official Synonym Symbols: MC3; OB20; OQTL; BMIQ9; MC3-R
• NCBI Protein Information: melanocortin receptor 3
• UniProt Protein Name: Melanocortin receptor 3
• Protein Family: Melanocortin receptor
• UniProt Gene Name: MC3R
• UniProt Synonym Gene Names: MC3-R
• UniProt Entry Name: MC3R_HUMAN

NCBI Description

This gene encodes a G-protein-coupled receptor for melanocyte-stimulating hormone and adrenocorticotropic hormone that is expressed in tissues other than the adrenal cortex and melanocytes. This gene maps to the same region as the locus for benign neonatal epilepsy. Mice deficient for this gene have increased fat mass despite decreased food intake, suggesting a role for this gene product in the regulation of energy homeostasis. Mutations in this gene are associated with a susceptibility to obesity in humans. [provided by RefSeq, Jul 2008]

Uniprot Description

MC3R: Receptor for MSH (alpha, beta and gamma) and ACTH. This receptor is mediated by G proteins which activate adenylate cyclase. Belongs to the G-protein coupled receptor 1 family.

Protein type: GPCR, family 1; Membrane protein, integral; Membrane protein, multi-pass; Receptor, GPCR

Chromosomal Location of Human Ortholog: 20q13.2-q13.3

Cellular Component: integral to plasma membrane; plasma membrane

Molecular Function: melanocortin receptor activity; melanocyte stimulating hormone receptor activity; neuropeptide binding; peptide hormone binding; protein binding

Biological Process: circadian regulation of gene expression; G-protein signaling, coupled to cAMP nucleotide second messenger; G-protein signaling, coupled to cyclic nucleotide second messenger; G-protein signaling, coupled to IP3 second messenger (phospholipase C activating); homoiothermy; locomotor rhythm; positive regulation of cAMP biosynthetic process; regulation of blood pressure; regulation of heart rate; sodium ion homeostasis

Disease: Body Mass Index Quantitative Trait Locus 9; Mycobacterium Tuberculosis, Susceptibility To