Aprotinin Active Protein
Aprotinin
Purity
> 95% (HPLC)
Synonyms
Aprotinin; Aprotinin active protein
Host
Bovine Lung
Purity/Purification
> 95% (HPLC)
Form/Format
Clear, Colorless Solution; 0.2 micron filtered solution in 0.9% sodium chloride and 0.9% benzyl alcohol.
Sequence Length
13
Protein
0.5-1.5 mg protein/mL (Biuret)
Specific Activity
> 5 TIU/mg protein
Activity
6-16 TIU/mL
CAS Number
9087-70-1
Preparation and Storage
Store at 2-8 degree C.
Related Product Information for Aprotinin active protein
The stability of the Aprotinin molecule is due to the 3 disulfide bonds linking the 6 cysteine members of the chain (Cys5-Cys55, Cys14-Cys38 and Cys30-Cys51). The lysine (15)-alanine (16) sequence on this strongly basic polypeptide represents the active center. A single chain polypeptide isolated from bovine lung with antifibrinolytic and anti-inflammatory activities. As a broad-spectrum serine protease inhibitor, aprotinin bovine competitively and reversibly inhibits the activity of a number of different esterases and proteases, including trypsin, chymotrypsin, kallikrein, plasmin, tissue plasminogen activator, and tissue and leukocytic proteinases, resulting in attenuation of the systemic inflammatory response (SIR), fibrinolysis, and thrombin generation. This agent also inhibits pro-inflammatory cytokine release and maintains glycoprotein homeostasis. Bovine Aprotinin REF: National Cancer Society/bovine/aprotinin.
NCBI and Uniprot Product Information
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Product Notes
The Aprotinin (Catalog #AAA173644) is an Active Protein produced from Bovine Lung and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "Aprotinin, Active Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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