SDS-Page
BOLA3 recombinant protein
BOLA3, 1-107aa, Human, His tag, E Coli
Gene Names
BOLA3; MMDS2
Applications
SDS-Page
Purity
> 95% by SDS-PAGE
Synonyms
BOLA3; 1-107aa; Human; His tag; E Coli; BolA-like protein 3 isoform1; MMDS2; BOLA3 recombinant protein
Host
E Coli
Purity/Purification
> 95% by SDS-PAGE
Form/Format
Liquid. In phosphate buffered saline (pH 7.4) containing 10% glycerol
Concentration
1mg/ml (determined by Absorbance at 280nm) (varies by lot)
Sequence
MGSSHHHHHH SSGLVPRGSH MGSMAAWSPA AAAPLLRGIR GLPLHHRMFA TQTEGELRVT QILKEKFPRA TAIKVTDISG GCGAMYEIKI ESEEFKEKRT VQQHQMVNQA LKEEIKEMHG LRIFTSVPKR
Sequence Length
107
Applicable Applications for BOLA3 recombinant protein
SDS-PAGE
Antigen Species
Human
Tag Information
His-tag
Preparation and Storage
Can be stored at 4 degree C short term (1-2 weeks).
For long term storage, aliquot and store at -20 degree C or -70 degree C.
Avoid repeated freezing and thawing cycles.
For long term storage, aliquot and store at -20 degree C or -70 degree C.
Avoid repeated freezing and thawing cycles.
SDS-Page
SDS-Page
Related Product Information for BOLA3 recombinant protein
BOLA3 also known as BolA-like protein 3 isoform1. BOLA3 is novel non-classical secreted protein and the secretion was not dependent on its predicted signal peptide. Human BolAs belongs to three different groups with functional divergence of BolA subfamily, where the different helix-turn-helix motif among BOLA 1, BOLA 2, and BOLA3 could be responsible for their functional divergence. Recombinant human BOLA3 was expressed in E Coli and purified by using conventional chromatography techniques.
Product Categories/Family for BOLA3 recombinant protein
References
Zhou Y.B., et al. (2008) Mol. Cell. Biochem. 317:61-68.; Cameron J.M., et al. (2011) Am. J. Hum. Genet. 89:486-495.;
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
14.5kDa (130aa) confirmed by MALDI-TOF
NCBI Official Full Name
bolA-like protein 3 isoform 1
NCBI Official Synonym Full Names
bolA family member 3
NCBI Official Symbol
BOLA3
NCBI Official Synonym Symbols
MMDS2
NCBI Protein Information
bolA-like protein 3
UniProt Protein Name
BolA-like protein 3
Protein Family
UniProt Gene Name
BOLA3
NCBI Description
This gene encodes a protein that plays an essential role in the production of iron-sulfur (Fe-S) clusters for the normal maturation of lipoate-containing 2-oxoacid dehydrogenases, and for the assembly of the mitochondrial respiratory chain complexes. Mutation in this gene has been associated with multiple mitochondrial dysfunctions syndrome-2. Two alternatively spliced transcript variants encoding different isoforms with distinct subcellular localization have been reported for this gene (PMID:21944046). [provided by RefSeq, Dec 2011]
Uniprot Description
Acts as a mitochondrial iron-sulfur (Fe-S) cluster assembly factor that facilitates (Fe-S) cluster insertion into a subset of mitochondrial proteins. Probably acts together with NFU1 (PubMed:27532772).
Research Articles on BOLA3
Similar Products
Product Notes
The BOLA3 bola3 (Catalog #AAA206117) is a Recombinant Protein produced from E Coli and is intended for research purposes only. The product is available for immediate purchase. The tag for this protein is His-tag. AAA Biotech's BOLA3 can be used in a range of immunoassay formats including, but not limited to, SDS-PAGE. Researchers should empirically determine the suitability of the BOLA3 bola3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: MGSSHHHHHH SSGLVPRGSH MGSMAAWSPA AAAPLLRGIR GLPLHHRMFA TQTEGELRVT QILKEKFPRA TAIKVTDISG GCGAMYEIKI ESEEFKEKRT VQQHQMVNQA LKEEIKEMHG LRIFTSVPKR. It is sometimes possible for the material contained within the vial of "BOLA3, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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