Protein BolA (bolA) Recombinant Protein | bolA recombinant protein
Recombinant Escherichia coli Protein BolA (bolA)
NCBI and Uniprot Product Information
NCBI Description
Although BolA is considered a transcriptional regulator, further characterization is needed to complete this assessment. [More information is available at EcoCyc: EG10125].
Uniprot Description
Transcriptional regulator that plays an important role in general stress response. Has many effects on cell morphology, cell growth and cell division. Acts by regulating the transcription of many genes, including dacA (PBP-5), dacC (PBP-6), ampC and mreB. Probably involved in the coordination of genes that adapt the cell physiology in order to enhance cell adaptation and survival under stress conditions. Essential for normal cell morphology in stationary phase and under conditions of starvation (PubMed:10361282, PubMed:12354237, PubMed:19111750, PubMed:21464593, PubMed:25691594). Also regulates a complex network of genes encoding proteins related to biofilm development, and negatively modulates flagellar biosynthesis and swimming capacity. Could be a motile/adhesive transcriptional switch, specifically involved in the transition between the planktonic and the attachment stage of biofilm formation (PubMed:25691594). Overexpression produces round cell shape, impairs cell growth rate and induces biofilm development (PubMed:305364, PubMed:15345459, PubMed:21464593).
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Product Notes
The bolA bola (Catalog #AAA1159157) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 1-105, full length protein. The amino acid sequence is listed below: MMIRERIEEK LRAAFQPVFL EVVDESYRHN VPAGSESHFK VVLVSDRFTG ERFLNRHRMI YSTLAEELST TVHALALHTY TIKEWEGLQD TVFASPPCRG AGSIA. It is sometimes possible for the material contained within the vial of "Protein BolA (bolA), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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