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BCL2/Adenovirus E1B 19kDa Interacting Protein 1 Recombinant Protein | BNIP1 recombinant protein

Recombinant Human BCL2/Adenovirus E1B 19kDa Interacting Protein 1

Gene Names
BNIP1; NIP1; SEC20; TRG-8
Purity
Greater than 95% as determined by SDS-PAGE.
Synonyms
BCL2/Adenovirus E1B 19kDa Interacting Protein 1; Recombinant Human BCL2/Adenovirus E1B 19kDa Interacting Protein 1; BNIP1 Human; BCL2/Adenovirus E1B 19kDa Interacting Protein 1 Human Recombinant; NIP1; BCL2/Adenovirus E1B 19 KDa Protein-Interacting Protein 1; Transformation-Related Gene 8 Protein; TRG-8; BCL2/Adenovirus E1B 19kD-Interacting Protein 1; Vesicle Transport Protein SEC20; SEC20L; SEC20; Vesicle transport protein SEC20; BNIP1 recombinant protein
Ordering
For Research Use Only!
Host
E Coli
Purity/Purification
Greater than 95% as determined by SDS-PAGE.
Form/Format
BNIP1 protein solution (1.0 mg/ml) containing 20mM Tris-HCl (pH8.0) and 10% glycerol.
Sterile filtered colorless solution.
Sequence
MGSSHHHHHH SSGLVPRGSH MGSMAAPQDV HVRICNQEIV KFDLEVKALI QDIRDCSGPL SALTELNTKVKEKFQQLRHR IQDLEQLAKE QDKESEKQLL LQEVENHKKQ MLSNQASWRK ANLTCKIAID NLEKAELLQGGDLLRQRKTT KESLAQTSST ITESLMGISR MMAQQVQQSEEAMQSLVTSS RTILDANEEF KSMSGTIQLG RKLITKYNRR EL
Sequence Length
228
Related Product Information for BNIP1 recombinant protein
Introduction: BNIP1 belongs to the of the BCL2/adenovirus E1B 19 kd-interacting protein (BNIP) family. BNIP1 interacts with the E1B 19 kDa protein, which defends cells from virally-induced cell death. In addition, BNIP1 interacts with E1B 19 kDa-like sequences of BCL2 which is an additional apoptotic protector. Adding up, BNIP1 is implicated in vesicle transport into the endoplasmic reticulum. Alternative splicing results of BNIP1 in four protein products with identical N- and C-termini have been found.

Description: BNIP1 Human Recombinant produced in E Coli is a single, non-glycosylated polypeptide chain containing 222 amino acids (1-199 a.a) and having a molecular mass of 25.2kDa. BNIP1 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
Product Categories/Family for BNIP1 recombinant protein

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
662
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
27,333 Da
NCBI Official Full Name
vesicle transport protein SEC20 isoform BNIP1
NCBI Official Synonym Full Names
BCL2/adenovirus E1B 19kDa interacting protein 1
NCBI Official Symbol
BNIP1
NCBI Official Synonym Symbols
NIP1; SEC20; TRG-8
NCBI Protein Information
vesicle transport protein SEC20
UniProt Protein Name
Vesicle transport protein SEC20
Protein Family
UniProt Gene Name
BNIP1
UniProt Synonym Gene Names
NIP1; SEC20L; TRG-8
UniProt Entry Name
SEC20_HUMAN

Uniprot Description

BNIP1: SNARE that may be involved in targeting and fusion of Golgi-derived retrograde transport vesicles with the ER. Required for maintenance of ER network. Implicated in the suppression of cell death. May be involved in mitochondrial autophagy. Belongs to the SEC20 family. 4 isoforms of the human protein are produced by alternative splicing.

Protein type: Apoptosis; Membrane protein, integral

Chromosomal Location of Human Ortholog: 5q33-q34

Cellular Component: cytoplasm; endoplasmic reticulum; endoplasmic reticulum membrane; integral to endoplasmic reticulum membrane; intracellular membrane-bound organelle; nuclear envelope; SNARE complex

Molecular Function: protein binding; SNAP receptor activity

Biological Process: apoptosis; endoplasmic reticulum membrane fusion; endoplasmic reticulum organization and biogenesis; negative regulation of apoptosis; retrograde vesicle-mediated transport, Golgi to ER

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Product Notes

The BNIP1 bnip1 (Catalog #AAA140583) is a Recombinant Protein produced from E Coli and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: MGSSHHH HHH SSGLVPRGSH MGSMAA PQDV HVRICNQEIV KFDLEVKALI QDIRDCSGPL SALTELNTKV KEKFQQLRHR IQDLEQLAKE QDKESEKQLL LQEVENHKKQ MLSNQASWRK ANLTCKIAID NLEKAELLQG GDLLRQRKTT KESLAQTSST ITESLMGISR MMAQQVQQSE EAMQSLVTSS RTILDANEEF KSMSGTIQLG RKLITKYNRR EL. It is sometimes possible for the material contained within the vial of "BCL2/Adenovirus E1B 19kDa Interacting Protein 1, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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