Neurofilament Medium Native Protein | bNEFM native protein
Bovine Neurofilament Medium Polypeptide
Gene Names
NEFM; NEF3; NF-M
Purity
Greater than 98.0% as determined by (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE.
Synonyms
Neurofilament Medium; Bovine Neurofilament Medium Polypeptide; NEFM; Neurofilament Medium Polypeptide Bovine; Neurofilament medium polypeptide; NF-M; Neurofilament triplet M protein; 160 kDa neurofilament protein; Neurofilament 3; NEF3; NFM; bNEFM native protein
Purity/Purification
Greater than 98.0% as determined by (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE.
Form/Format
The protein was lyophilized from a 1mg/ml solution containing 10mM sodium phosphate, pH-7.5, 2mM DTT, 6M urea and 1mM EDTA.
Sterile Filtered White lyophilized (freeze-dried) powder.
Sterile Filtered White lyophilized (freeze-dried) powder.
Source
Bovine Spinal Cord
Solubility
It is recommended to reconstitute the lyophilized NEFM in sterile 18M Omega-cm H2O.
Preparation and Storage
Lyophilized NEFM although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution NEFM should be stored at 4°C between 2-7 days and for future use below -18°C.
Please prevent freeze-thaw cycles.
Please prevent freeze-thaw cycles.
Related Product Information for bNEFM native protein
Description: Ultra Pure NeuroFilament Protein having a Molecular mass of 160 kDa produced from Bovine Spinal Cord.
Introduction: Neurofilaments are type IV intermediate filament heteropolymers that are composed of light, medium, and heavy chains. Neurofilaments comprise the axoskeleton and functionally maintain neuronal caliber and may also have a role in intracellular transport to axons and dendrites. NeuroFilament 160kDa is a medium neurofilament protein, which is commonly used as a biomarker of neuronal damage.
Introduction: Neurofilaments are type IV intermediate filament heteropolymers that are composed of light, medium, and heavy chains. Neurofilaments comprise the axoskeleton and functionally maintain neuronal caliber and may also have a role in intracellular transport to axons and dendrites. NeuroFilament 160kDa is a medium neurofilament protein, which is commonly used as a biomarker of neuronal damage.
Product Categories/Family for bNEFM native protein
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
UniProt Accession #
NCBI Official Full Name
Neurofilament medium polypeptide
NCBI Official Synonym Full Names
neurofilament, medium polypeptide
NCBI Official Symbol
NEFM
NCBI Official Synonym Symbols
NEF3; NF-M
NCBI Protein Information
neurofilament medium polypeptide; 160 kDa neurofilament protein; major neuronal intermediate filament subunit; neurofilament 3; neurofilament M subunit; neurofilament triplet M protein
UniProt Protein Name
Neurofilament medium polypeptide
Protein Family
UniProt Gene Name
NEFM
UniProt Synonym Gene Names
NEF3; NFM; NF-M
UniProt Entry Name
NFM_BOVIN
Uniprot Description
NFM: a neurofilament intermediate filament protein. Neurofilaments usually contain three intermediate filament proteins: L, M, and H which are involved in the maintenance of neuronal caliber. The levels of phosphorylation are altered developmentally and coincident with a change in the neurofilament function.
Protein type: Cytoskeletal
Cellular Component: neurofilament
Molecular Function: structural molecule activity
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Product Notes
The bNEFM nefm (Catalog #AAA143075) is a Native Protein and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "Neurofilament Medium, Native Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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