BMP3 recombinant protein

BMP3 protein

Cat. Num. AAA5304438

• Gene Names: BMP3; BMP-3A
• Purity: > 98% pure; BMP3 protein was purified using a a proprietary chromatographic technique.
• Synonyms: BMP3; BMP3 protein; Bone morphogenetic protein 3 protein; Osteogenin protein; BMP 3 protein; BMP-3; BMP 3; BMP-3A protein; BMP-3 protein; BMP3 recombinant protein

• Host: Human
• Purity/Purification: > 98% pure; BMP3 protein was purified using a a proprietary chromatographic technique.
• Form/Format: Supplied in lyophilized form with no additives
• Sequence Length: 472

• Protein Type: Recombinant
• Biological Significance: BMPs belong to the TGF beta superfamily of structurally related signaling proteins. As implied by their name, BMPs promote and regulate bone development, growth, remodeling and repair, in both prenatal development and postnatal growth of eye, heart, kidney, skin, and other tissues.
• Endotoxin Levels: <0.1 ng/ug
• Expression System: E Coli
• Preparation and Storage: Store at 4 degree C for short term storage. Aliquot and store at -20 degree C for long term storage. Avoid repeated freeze/thaw cycles.

Related Product Information for BMP3 recombinant protein

Purified recombinant Human BMP3 protein

Product Categories/Family for BMP3 recombinant protein

Cytokines & Growth Factors

NCBI and Uniprot Product Information

• NCBI GI #: 126507087
• NCBI GeneID: 651
• NCBI Accession #: NP_001192.2
• NCBI GenBank Nucleotide #: NM_001201.2
• Molecular Weight: 31.6 kDa
• NCBI Official Full Name: bone morphogenetic protein 3 preproprotein
• NCBI Official Synonym Full Names: bone morphogenetic protein 3
• NCBI Official Symbol: BMP3
• NCBI Official Synonym Symbols: BMP-3A
• NCBI Protein Information: bone morphogenetic protein 3
• UniProt Protein Name: Bone morphogenetic protein 3
• Protein Family: Bone morphogenetic protein
• UniProt Gene Name: BMP3
• UniProt Synonym Gene Names: BMP3A; BMP-3; BMP-3A
• UniProt Entry Name: BMP3_HUMAN

NCBI Description

BMP3 belongs to the transforming growth factor-beta (TGFB) superfamily. Bone morphogenic protein, also known as osteogenin, induces bone formation. [provided by RefSeq, Jul 2008]

Uniprot Description

BMP3: Negatively regulates bone density. Antagonizes the ability of certain osteogenic BMPs to induce osteoprogenitor differentitation and ossification. Belongs to the TGF-beta family.

Protein type: Cytokine; Secreted; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 4q21

Cellular Component: extracellular space

Molecular Function: growth factor activity; cytokine activity; transforming growth factor beta receptor binding; receptor binding

Biological Process: regulation of apoptosis; ossification; cell-cell signaling; regulation of MAPKKK cascade; cartilage development; positive regulation of transcription from RNA polymerase II promoter; skeletal development; cell development; growth