ZIS blocking peptide
ZIS (I144) Peptide
Applications
Blocking
Purity
Synthetic peptide ZIS (I144). (Note: the amino acid sequence is proprietary).The purity is >98%.
Synonyms
ZIS; ZIS (I144) Peptide; ZRANB 2; Zinc finger protein 265; Zinc finger RAN binding domain containing 2; Zinc finger Ran binding domain containing protein 2; Zinc finger splicing; ZIS1; ZIS2; ZNF265; ZIS blocking peptide
Specificity
This peptide can be used with studies using MBS3001844 ZIS (I144) pAb.
Purity/Purification
Synthetic peptide ZIS (I144). (Note: the amino acid sequence is proprietary).
The purity is >98%.
The purity is >98%.
Form/Format
1 mg/ml in DI water.
Sequence Length
320
Applicable Applications for ZIS blocking peptide
Blocking
Preparation and Storage
Store at 4 degree C short term.
Aliquot and store at -20 degree C long term.
Avoid freeze-thaw cycles.
Aliquot and store at -20 degree C long term.
Avoid freeze-thaw cycles.
Related Product Information for ZIS blocking peptide
Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. ZNF265 (Zinc finger protein 265), also known as ZRANB2 (Zinc finger Ran-binding domain-containing protein 2), ZIS, ZIS1 or ZIS2, is a 330 amino acid protein that belongs to the ZRANB2 family. Localized to the nucleus, ZNF265 functions as a splicing factor that is responsible for alternatively splicing Tra-2beta (transformer-2 beta) transcripts and is thought to interfere with constitutive 5-splice selection. ZNF265 contains two RanBP2-type zinc fingers through which it conveys its RNA-binding activity. Two isoforms, designated ZIS-1 and ZIS-2, are expressed due to alternative splicing events. Upon DNA damage, ZIS-2 may be phosphorylated by ATM or ATR.
NCBI and Uniprot Product Information
NCBI GI #
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
NCBI Official Full Name
zinc finger Ran-binding domain-containing protein 2 isoform 2
UniProt Protein Name
Zinc finger Ran-binding domain-containing protein 2
Protein Family
UniProt Gene Name
ZRANB2
UniProt Synonym Gene Names
ZIS; ZNF265
UniProt Entry Name
ZRAB2_HUMAN
Uniprot Description
ZNF265: Splice factor required for alternative splicing of TRA2B/SFRS10 transcripts. May interfere with constitutive 5'- splice site selection. Belongs to the ZRANB2 family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: RNA-binding
Chromosomal Location of Human Ortholog: 1p31
Cellular Component: nucleoplasm; nucleus
Molecular Function: protein binding; zinc ion binding; RNA binding; transcription factor activity
Biological Process: regulation of transcription, DNA-dependent; RNA splicing; mRNA processing
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Product Notes
The ZIS zranb2 (Catalog #AAA3001845) is a Blocking Peptide and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's ZIS can be used in a range of immunoassay formats including, but not limited to, Blocking. Researchers should empirically determine the suitability of the ZIS zranb2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "ZIS, Blocking Peptide" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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