WNT9B blocking peptide

WNT9B Blocking Peptide

Cat. Num. AAA9628066

• Gene Names: WNT9B; WNT15; WNT14B
• Applications: Blocking/Control
• Purity: The purity is >90%,tested by HPLC and MS.
• Synonyms: WNT9B; WNT9B Blocking Peptide; MGC124412; Protein Wnt 9b precursor; Protein Wnt-14b; Protein Wnt-9b; Wingless type MMTV integration site 9B; Wingless type MMTV integration site family member 15; Wingless type MMTV integration site family member 9B; Wnt 14b; Wnt-15; Wnt14b; Wnt15; Wnt9b wingless type MMTV integration site family member 9B; WNT9B blocking peptide

• Purity/Purification: The purity is >90%,tested by HPLC and MS.
• Form/Format: Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 10 mg/ml.

• Applicable Applications for WNT9B blocking peptide: Blocking/Control
• Notes: For phospho antibody, we provide phospho peptide (0.5mg) and non-phospho peptide (0.5mg)
• Preparation and Storage: Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C.

Related Product Information for WNT9B blocking peptide

Blocking peptides are peptides that bind specifically to the target antibody and block antibody binding. These peptide usually contains the epitope recognized by the antibody. Antibodies bound to the blocking peptide no longer bind to the epitope on the target protein. This mechanism is useful when non-specific binding is an issue, for example, in Western blotting (immunoblot) and immunohistochemistry (IHC). By comparing the staining from the blocked antibody versus the antibody alone, one can see which staining is specific; Specific binding will be absent from the western blot or immunostaining performed with the neutralized antibody.

NCBI and Uniprot Product Information

• NCBI GI #: 17017976
• NCBI GeneID: 7484
• NCBI Accession #: NP_003387.1
• NCBI GenBank Nucleotide #: NM_003396.2
• UniProt Accession #: O14905; Q6UXT4; Q96Q09
• Molecular Weight: 39,001 Da
• NCBI Official Full Name: protein Wnt-9b
• NCBI Official Synonym Full Names: wingless-type MMTV integration site family, member 9B
• NCBI Official Symbol: WNT9B
• NCBI Official Synonym Symbols: WNT15; WNT14B
• NCBI Protein Information: protein Wnt-9b; protein Wnt-14b; wingless-type MMTV integration site family, member 15
• UniProt Protein Name: Protein Wnt-9b
• Protein Family: Protein
• UniProt Gene Name: WNT9B
• UniProt Synonym Gene Names: WNT14B; WNT15
• UniProt Entry Name: WNT9B_HUMAN

NCBI Description

The WNT gene family consists of structurally related genes that encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. Study of its expression in the teratocarcinoma cell line NT2 suggests that it may be implicated in the early process of neuronal differentiation of NT2 cells induced by retinoic acid. This gene is clustered with WNT3, another family member, in the chromosome 17q21 region. [provided by RefSeq, Jul 2008]

Uniprot Description

WNT9B: Ligand for members of the frizzled family of seven transmembrane receptors. Probable developmental protein. May be a signaling molecule which affects the development of discrete regions of tissues. Is likely to signal over only few cell diameters. Belongs to the Wnt family.

Protein type: Secreted, signal peptide; Secreted

Chromosomal Location of Human Ortholog: 17q21

Cellular Component: extracellular space; proteinaceous extracellular matrix; extracellular region

Molecular Function: frizzled binding

Biological Process: positive regulation of catalytic activity; regulation of protein amino acid phosphorylation; Wnt receptor signaling pathway; cell fate commitment; response to retinoic acid; regulation of asymmetric cell division; in utero embryonic development; Wnt receptor signaling pathway, planar cell polarity pathway; multicellular organismal development; palate development; Wnt receptor signaling pathway through beta-catenin; embryonic cranial skeleton morphogenesis; cellular response to starvation; neuron differentiation; cell-cell signaling; ureteric bud branching; male genitalia development; regulation of tube size