VTI1B blocking peptide

VTI1B Blocking Peptide

Gene Names

VTI1B; VTI1; VTI2; VTI1L; v-SNARE; vti1-rp1; VTI1-LIKE

Applications

Blocking/Control

Purity

The purity is >90%,tested by HPLC and MS.

Synonyms

VTI1B; VTI1B Blocking Peptide; HGNC:17793; V SNARE; v-SNARE; Vesicle associated soluble NSF attachment protein receptor; Vesicle transport through interaction with t SNAREs 1B; Vesicle transport through interaction with t SNAREs homolog 1B (yeast); Vesicle transport through interaction with t-SNAREs homolog 1B; Vesicle transport v-SNARE protein Vti1-like 1; VTI1; VTI1 like; Vti1 rp1; VTI1-LIKE; Vti1-rp1; VTI1B_HUMAN; VTI1L; VTI1L1; VTI2; VTI1B blocking peptide

Ordering
Cat. Num. AAA9624781 For Research Use Only!

Purity/Purification

The purity is >90%,tested by HPLC and MS.

Form/Format

Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 10 mg/ml.

Applicable Applications for VTI1B blocking peptide

Blocking/Control

Notes

For phospho antibody, we provide phospho peptide (0.5mg) and non-phospho peptide (0.5mg)

Preparation and Storage

Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C.

Related Product Information for VTI1B blocking peptide

Blocking peptides are peptides that bind specifically to the target antibody and block antibody binding. These peptide usually contains the epitope recognized by the antibody. Antibodies bound to the blocking peptide no longer bind to the epitope on the target protein. This mechanism is useful when non-specific binding is an issue, for example, in Western blotting (immunoblot) and immunohistochemistry (IHC). By comparing the staining from the blocked antibody versus the antibody alone, one can see which staining is specific; Specific binding will be absent from the western blot or immunostaining performed with the neutralized antibody.

NCBI and Uniprot Product Information

NCBI GI #

5454166

NCBI GeneID

10490

NCBI Accession #

NP_006361.1

NCBI GenBank Nucleotide #

NM_006370.2

UniProt Accession #

Q9UEU0; O43547; Q96J28

Molecular Weight

26,688 Da

NCBI Official Full Name

vesicle transport through interaction with t-SNAREs homolog 1B

NCBI Official Synonym Full Names

vesicle transport through interaction with t-SNAREs 1B

NCBI Official Symbol

VTI1B

NCBI Official Synonym Symbols

VTI1; VTI2; VTI1L; v-SNARE; vti1-rp1; VTI1-LIKE

NCBI Protein Information

vesicle transport through interaction with t-SNAREs homolog 1B; vesicle transport v-SNARE protein Vti1-like 1; vesicle-associated soluble NSF attachment protein receptor

UniProt Protein Name

Vesicle transport through interaction with t-SNAREs homolog 1B

Protein Family

Vesicle transport through interaction with t-SNAREs

UniProt Gene Name

VTI1B

UniProt Synonym Gene Names

VTI1; VTI1L; VTI1L1; VTI2

UniProt Entry Name

VTI1B_HUMAN

Uniprot Description

VTI1B: V-SNARE that mediates vesicle transport pathways through interactions with t-SNAREs on the target membrane. These interactions are proposed to mediate aspects of the specificity of vesicle trafficking and to promote fusion of the lipid bilayers. May be concerned with increased secretion of cytokines associated with cellular senescence. Belongs to the VTI1 family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Vesicle; Membrane protein, integral

Chromosomal Location of Human Ortholog: 14q24.1

Cellular Component: SNARE complex; Golgi apparatus; endoplasmic reticulum membrane; recycling endosome; synaptic vesicle; cell soma; intracellular membrane-bound organelle; late endosome membrane; lysosomal membrane; perinuclear region of cytoplasm; cytoplasm; integral to membrane; vesicle

Molecular Function: SNAP receptor activity; SNARE binding; chloride channel inhibitor activity

Biological Process: vesicle-mediated transport; cell proliferation; intra-Golgi vesicle-mediated transport; ER to Golgi vesicle-mediated transport; autophagic vacuole fusion; Golgi to vacuole transport; vesicle fusion with Golgi apparatus; protein targeting to vacuole; retrograde transport, endosome to Golgi; vesicle docking during exocytosis

Research Articles on VTI1B

1. Vti1b-dependent tethering of Lytic granule and CD3-endo determines accumulation, docking, and efficient lytic granule secretion at the immunological synapse.

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Product Notes

The VTI1B vti1b (Catalog #AAA9624781) is a Blocking Peptide and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's VTI1B can be used in a range of immunoassay formats including, but not limited to, Blocking/Control. Researchers should empirically determine the suitability of the VTI1B vti1b for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "VTI1B, Blocking Peptide" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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VTI1B blocking peptide