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TRIM56 blocking peptide

TRIM56 Antibody (C-term) Blocking peptide

Gene Names
TRIM56; RNF109
Synonyms
TRIM56; TRIM56 Antibody (C-term) Blocking peptide; E3 ubiquitin-protein ligase TRIM56; 632-; RING finger protein 109; Tripartite motif-containing protein 56; RNF109; TRIM56 blocking peptide
Ordering
Form/Format
Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
Sequence Length
755
Cellular Location
Cytoplasm.
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C.
Related Product Information for TRIM56 blocking peptide
E3 ubiquitin-protein ligase that mediates 'Lys-63'- linked polyubiquitination of TMEM173/STING, thereby playing a key role in innate immunity. TMEM173/STING 'Lys-63'-linked ubiquitination activates the production of type I interferon IFN- beta following detection of pathogen- and host-derived double- stranded DNA (By similarity).

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
UniProt Accession #
Molecular Weight
29,185 Da
NCBI Official Full Name
E3 ubiquitin-protein ligase TRIM56
NCBI Official Synonym Full Names
tripartite motif containing 56
NCBI Official Symbol
TRIM56
NCBI Official Synonym Symbols
RNF109
NCBI Protein Information
E3 ubiquitin-protein ligase TRIM56
UniProt Protein Name
E3 ubiquitin-protein ligase TRIM56
UniProt Gene Name
TRIM56
UniProt Synonym Gene Names
RNF109
UniProt Entry Name
TRI56_HUMAN

Uniprot Description

TRIM56: E3 ubiquitin-protein ligase that mediates 'Lys-63'- linked polyubiquitination of TMEM173/STING, thereby playing a key role in innate immunity. TMEM173/STING 'Lys-63'-linked ubiquitination activates the production of type I interferon IFN- beta following detection of pathogen- and host-derived double- stranded DNA. Belongs to the TRIM/RBCC family. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: RNA-binding; Ubiquitin conjugating system; EC 6.3.2.-

Chromosomal Location of Human Ortholog: 7q22.1

Cellular Component: cytoplasm; cytosol

Molecular Function: ubiquitin-protein ligase activity

Biological Process: defense response to virus; interferon-beta production; regulation of interferon type I production

Research Articles on TRIM56

Similar Products

Product Notes

The TRIM56 trim56 (Catalog #AAA9218652) is a Blocking Peptide and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "TRIM56, Blocking Peptide" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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