Trim30 blocking peptide
TRIM30 Peptide
NCBI and Uniprot Product Information
Uniprot Description
TRIM30A: Trans-acting factor that regulates gene expression of interleukin 2 receptor alpha chain. May affect IL2R-alpha expression through cis-acting negative regulatory elements or through competition with proteins that bind to enhancer or activator sequences. Negatively regulates Toll-like receptor (TLR)-mediated activation of NFKB by promoting degradation of TAB2 and TAB3 and preventing TRAF6 autoubiquitination. Negatively regulates production of reactive oxygen species (ROS) which inhibits activation of the NLRP3 inflammasome complex. This, in turn, regulates activation of CASP1 and subsequent cleavage of IL1B and IL18. No activity detected against a range of retroviruses including a number of lentiviruses, gammaretroviruses and betaretroviruses
Cellular Component: cytoplasm; intracellular; nucleus
Molecular Function: DNA binding; zinc ion binding; metal ion binding
Biological Process: protein autoubiquitination; regulation of transcription, DNA-dependent; transcription, DNA-dependent; positive regulation of virion penetration into host cell; negative regulation of toll-like receptor signaling pathway; positive regulation of protein catabolic process; negative regulation of interleukin-6 production; negative regulation of tumor necrosis factor production
Research Articles on Trim30
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Product Notes
The Trim30 trim30a (Catalog #AAA152532) is a Blocking Peptide and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's TRIM30 can be used in a range of immunoassay formats including, but not limited to, Blocking (BL). TRIM30 peptide is used for blocking the activity of TRIM30 antibody. Researchers should empirically determine the suitability of the Trim30 trim30a for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "TRIM30, Blocking Peptide" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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