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TRHDE blocking peptide

TRHDE Antibody (C-term) Blocking peptide

Gene Names
TRHDE; PAP-II; PGPEP2; TRH-DE
Synonyms
TRHDE; TRHDE Antibody (C-term) Blocking peptide; Thyrotropin-releasing hormone-degrading ectoenzyme; TRH-DE; TRH-degrading ectoenzyme; Pyroglutamyl-peptidase II; PAP-II; TRH-specific aminopeptidase; Thyroliberinase; TRHDE blocking peptide
Ordering
Form/Format
Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
Sequence Length
1024
Cellular Location
Membrane; Single-pass type II membrane protein
Tissue Location
Predominantly expressed in brain.
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C.
Related Product Information for TRHDE blocking peptide
Specific inactivation of TRH after its release.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
117,000 Da
NCBI Official Full Name
thyrotropin-releasing hormone-degrading ectoenzyme
NCBI Official Synonym Full Names
thyrotropin releasing hormone degrading enzyme
NCBI Official Symbol
TRHDE
NCBI Official Synonym Symbols
PAP-II; PGPEP2; TRH-DE
NCBI Protein Information
thyrotropin-releasing hormone-degrading ectoenzyme
UniProt Protein Name
Thyrotropin-releasing hormone-degrading ectoenzyme
UniProt Gene Name
TRHDE
UniProt Synonym Gene Names
TRH-DE; TRH-degrading ectoenzyme; PAP-II
UniProt Entry Name
TRHDE_HUMAN

NCBI Description

This gene encodes a member of the peptidase M1 family. The encoded protein is an extracellular peptidase that specifically cleaves and inactivates the neuropeptide thyrotropin-releasing hormone.[provided by RefSeq, Dec 2008]

Uniprot Description

TRHDE: Specific inactivation of TRH after its release. Belongs to the peptidase M1 family.

Protein type: Protease; EC 3.4.19.6; Membrane protein, integral

Chromosomal Location of Human Ortholog: 12q15-q21

Cellular Component: cytoplasm; integral to plasma membrane

Molecular Function: aminopeptidase activity; peptide binding; zinc ion binding

Biological Process: cell-cell signaling; peptide catabolic process; regulation of blood pressure; signal transduction

Research Articles on TRHDE

Similar Products

Product Notes

The TRHDE trhde (Catalog #AAA9225719) is a Blocking Peptide and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "TRHDE, Blocking Peptide" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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