TMF1 blocking peptide

TMF1 Blocking Peptide (Center)

Gene Names

TMF1; TMF; ARA160

Synonyms

TMF1; TMF1 Blocking Peptide (Center); TATA element modulatory factor; TMF; Androgen receptor coactivator 160 kDa protein; Androgen receptor-associated protein of 160 kDa; ARA160; TMF1 blocking peptide

Ordering

Specificity

The synthetic peptide sequence is selected from aa 467-480 of HUMAN TMF1

Form/Format

Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.

Sequence Length

1093

Cellular Location

Cytoplasm. Nucleus. Golgi apparatus membrane. Note: Concentrated at the budding structures localized at the tips of cisternae

Preparation and Storage

Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C.

Related Product Information for TMF1 blocking peptide

Potential coactivator of the androgen receptor. Mediates STAT3 degradation. May play critical roles in two RAB6-dependent retrograde transport processes: one from endosomes to the Golgi and the other from the Golgi to the ER. This protein binds the HIV-1 TATA element and inhibits transcriptional activation by the TATA-binding protein (TBP).

NCBI and Uniprot Product Information

NCBI GI #

218511858

NCBI GeneID

7110

UniProt Accession #

P82094; Q17R87; Q59GK0; B7ZLJ2

Molecular Weight

123,155 Da

NCBI Official Full Name

TATA element modulatory factor

NCBI Official Synonym Full Names

TATA element modulatory factor 1

NCBI Official Symbol

TMF1

NCBI Official Synonym Symbols

TMF; ARA160

NCBI Protein Information

TATA element modulatory factor

UniProt Protein Name

TATA element modulatory factor

Protein Family

TATA element modulatory factor

UniProt Gene Name

TMF1

UniProt Synonym Gene Names

ARA160; TMF

UniProt Entry Name

TMF1_HUMAN

Uniprot Description

TMF1: Potential coactivator of the androgen receptor. Mediates STAT3 degradation. May play critical roles in two RAB6-dependent retrograde transport processes: one from endosomes to the Golgi and the other from the Golgi to the ER. This protein binds the HIV-1 TATA element and inhibits transcriptional activation by the TATA-binding protein (TBP). 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Nuclear receptor co-regulator; Transcription factor

Chromosomal Location of Human Ortholog: 3p14.1

Cellular Component: cytosol; Golgi apparatus

Molecular Function: protein binding; transcription cofactor activity

Biological Process: transcription from RNA polymerase II promoter

Research Articles on TMF1

1. In patient with chronic granulomatous disease, a 5.8-kb, incomplete and partly exonized TMF1 transcript was identified in intron 1 of CYBB, in opposite orientation to the host gene.

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Product Notes

The TMF1 tmf1 (Catalog #AAA9230447) is a Blocking Peptide and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "TMF1, Blocking Peptide" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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TMF1 blocking peptide