TIMM10 blocking peptide

TIMM10 Antibody (Center) Blocking Peptide

• Gene Names: TIMM10; TIM10; TIM10A
• Synonyms: TIMM10; TIMM10 Antibody (Center) Blocking Peptide; Mitochondrial import inner membrane translocase subunit Tim10; TIM10; TIMM10 blocking peptide

• Form/Format: Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
• Sequence Length: 90

• Cellular Location: Mitochondrion inner membrane; Peripheral membrane protein; Intermembrane side
• Tissue Location: Ubiquitous, with highest expression in heart, kidney, liver and skeletal muscle.
• Preparation and Storage: Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C.

Related Product Information for TIMM10 blocking peptide

Mitochondrial intermembrane chaperone that participates in the import and insertion of multi-pass transmembrane proteins into the mitochondrial inner membrane. May also be required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space.

NCBI and Uniprot Product Information

• NCBI GI #: 49065657
• NCBI GeneID: 26519
• UniProt Accession #: P62072; Q9WV99; Q9WVA0; Q9Y5J8; A8K136
• Molecular Weight: 10,333 Da
• NCBI Official Full Name: Mitochondrial import inner membrane translocase subunit Tim10
• NCBI Official Synonym Full Names: translocase of inner mitochondrial membrane 10 homolog (yeast)
• NCBI Official Symbol: TIMM10
• NCBI Official Synonym Symbols: TIM10; TIM10A
• NCBI Protein Information: mitochondrial import inner membrane translocase subunit Tim10
• UniProt Protein Name: Mitochondrial import inner membrane translocase subunit Tim10
• UniProt Gene Name: TIMM10
• UniProt Synonym Gene Names: TIM10
• UniProt Entry Name: TIM10_HUMAN

NCBI Description

The mitochondrial protein encoded by this gene belongs to a family of evolutionarily conserved proteins that are organized in heterooligomeric complexes in the mitochondrial intermembrane space. These proteins mediate the import and insertion of hydrophobic membrane proteins into the mitochondrial inner membrane, functioning as intermembrane space chaperones for the highly insoluble carrier proteins. [provided by RefSeq, Nov 2011]

Uniprot Description

TIMM10: Mitochondrial intermembrane chaperone that participates in the import and insertion of multi-pass transmembrane proteins into the mitochondrial inner membrane. May also be required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space. Belongs to the small Tim family.

Protein type: Mitochondrial

Chromosomal Location of Human Ortholog: 11q12.1

Cellular Component: mitochondrial inner membrane; mitochondrial inner membrane presequence translocase complex; mitochondrial intermembrane space; mitochondrial intermembrane space protein transporter complex; mitochondrion

Molecular Function: chaperone binding; protein binding; protein homodimerization activity; protein transporter activity; transporter activity; zinc ion binding

Biological Process: protein import into mitochondrial inner membrane; protein targeting to mitochondrion; sensory perception of sound