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TGOLN2 blocking peptide

TGOLN2 Antibody (C-term) Blocking Peptide

Gene Names
TGOLN2; TGN38; TGN46; TGN48; TGN51; TTGN2
Synonyms
TGOLN2; TGOLN2 Antibody (C-term) Blocking Peptide; Trans-Golgi network integral membrane protein 2; TGN38 homolog; TGN46; TGN48; Trans-Golgi network protein TGN51; TGN51; TGOLN2 blocking peptide
Ordering
Specificity
The synthetic peptide sequence used to generate the antibody was selected from the C-term region of human TGOLN2. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Form/Format
Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
Sequence Length
480
Cellular Location
Cell membrane; Single-pass type I membrane protein. Golgi apparatus, trans-Golgi network membrane; Single- pass type I membrane protein. Note: Primarily in trans-Golgi network. Cycles between the trans-Golgi network and the cell surface returning via endosomes
Tissue Location
Isoform TGN46 is widely expressed. Isoform TGN51 is more abundant in fetal lung and kidney. Isoform TGN48 is barely expressed in embryonic kidney and promyelocytic cells
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C.
Related Product Information for TGOLN2 blocking peptide
May be involved in regulating membrane traffic to and from trans-Golgi network.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
Molecular Weight
29,541 Da
NCBI Official Full Name
Trans-Golgi network integral membrane protein 2
NCBI Official Synonym Full Names
trans-golgi network protein 2
NCBI Official Symbol
TGOLN2
NCBI Official Synonym Symbols
TGN38; TGN46; TGN48; TGN51; TTGN2
NCBI Protein Information
trans-Golgi network integral membrane protein 2
UniProt Protein Name
Trans-Golgi network integral membrane protein 2
UniProt Gene Name
TGOLN2
UniProt Synonym Gene Names
TGN46; TGN51
UniProt Entry Name
TGON2_HUMAN

NCBI Description

This gene encodes a type I integral membrane protein that is localized to the trans-Golgi network, a major sorting station for secretory and membrane proteins. The encoded protein cycles between early endosomes and the trans-Golgi network, and may play a role in exocytic vesicle formation. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Oct 2011]

Uniprot Description

TGOLN2: May be involved in regulating membrane traffic to and from trans-Golgi network. 6 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral

Chromosomal Location of Human Ortholog: 2p11.2

Cellular Component: endosome; Golgi apparatus; nucleoplasm; trans-Golgi network; trans-Golgi network membrane; trans-Golgi network transport vesicle; transport vesicle

Molecular Function: protein binding

Biological Process: Golgi to endosome transport

Research Articles on TGOLN2

Similar Products

Product Notes

The TGOLN2 tgoln2 (Catalog #AAA9227944) is a Blocking Peptide and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "TGOLN2, Blocking Peptide" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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